Free NFL Week 3 Pick: 49ers vs. Rams Odds
Looking for San Francisco 49ers vs. Los Angeles Rams free NFL picks & NFL odds? NFL betting sees the 49ers taking on the Rams on Sunday, September 22nd at the SoFi Stadium. Cappers Picks provides complimentary NFL Football handicapping picks all NFL season long including all NFL Week 3 games so stay tuned for more FREE NFL predictions like this San Francisco Los Angeles matchup.
NFL Handicapping Analysis: Week 3
(1-1) San Francisco 49ers vs. Los Angeles Rams (0-2)
Date: Sunday, September 22nd
Time: 4:25 ET
Venue: SoFi Stadium, Inglewood CA
NFL ATS Betting Lines: (BET NOW!) San Francisco -7 | Los Angeles +7
NFL Moneyline Odds: San Francisco -349 | Los Angeles +276
NFL Betting Total: O/U 43.5
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Get ready, folks—Week 3 is about to heat up as the San Francisco 49ers (1-1) head to SoFi Stadium to take on the winless Los Angeles Rams (0-2). The stakes? High as ever, with the loser likely finding themselves in the NFC West cellar. The betting lines are set, with San Francisco laying a touchdown as 7-point favorites, but this game is far from a sure thing.
Yes, the 49ers have owned this head-to-head matchup, going 9-2 outright in their last 11 battles with the Rams. But here’s where things get spicy: Both teams are limping into this one with key players on the shelf. The Niners are without Christian McCaffrey and Deebo Samuel, while the Rams will be missing Cooper Kupp and breakout star Puka Nacua.
Each team picked up a win on the road in the two-game series between the 49ers and Rams last year.
The 49ers won the first game 30-23, while the Rams took the second game 21-20.
San Francisco was favored by -7 in the first game and -5.5 in the second, and the over/under lines were 45 points in the first game and 40 points in the second, with both games going over, finishing with 53 and 41 combined points, respectively.
San Francisco 49ers
The 49ers’ record is now 1-1 after their 23-17 loss to the Vikings. San Francisco fell behind early, with the Vikings taking a 3-0 lead in the 1st quarter. The 49ers managed to score a touchdown in the 2nd quarter, but they still trailed 13-7 at halftime. Failing to score in the 3rd quarter, the 49ers entered the 4th quarter down 20-7.
In the 4th quarter, the 49ers made a push, with Brock Purdy connecting with George Kittle for a touchdown and adding a 10-yard touchdown pass to Kittle. However, the Vikings also scored in the 4th quarter, making it tough for the 49ers to complete the comeback. Despite the loss, the 49ers did manage to score with 1:15 remaining in the 4th quarter, as Jordan Mason rushed for a touchdown.
San Francisco 49ers Stats
The 49ers’ offense had 24 first downs in their 23-17 loss to the Vikings, with a total of 403 yards. They struggled on third down, converting only 20% of their chances, and their offensive line allowed six sacks. Brock Purdy threw for 319 yards, completing 77% of his passes, with one touchdown and one interception.
Jordan Mason rushed for 100 yards to lead the team, averaging 5 yards per attempt and scoring one touchdown. Deebo Samuel Sr. was the top receiver, with 110 yards on eight catches.
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In their 23-17 loss to the Vikings, the 49ers’ defense allowed 146 rushing yards on just 24 attempts, giving up big plays in the running game (6.1 yards per attempt). Despite forcing one interception and recording four sacks, they struggled to get off the field, allowing the Vikings to convert 58.3% of their third down attempts.
In the passing game, the 49ers allowed 257 yards and two touchdowns, with Minnesota averaging 9.9 yards per attempt. San Francisco’s defense will need to improve in defending the run and limiting explosive plays in the passing game moving forward.
Los Angeles Rams
The Rams are now 0-2 after a 41-10 loss to the Cardinals in their most recent game. Los Angeles fell behind quickly, trailing 14-0 after the 1st quarter and 24-3 at halftime. The Rams’ only touchdown came with 44 seconds left in the 3rd quarter, while the Cardinals added a touchdown in the 4th quarter to secure the blowout win.
Marvin Harrison Jr. caught two touchdown passes from Kyler Murray in the 1st quarter, and the Cardinals kept extending their lead. James Conner and Kyren Williams also found the endzone for Arizona, while the Rams couldn’t get anything going offensively after their 3rd quarter touchdown.
Los Angeles Rams Stats
The Rams’ offense struggled to sustain drives in their 41-10 loss to the Cardinals, managing just 14 first downs and going 1-for-5 in the red zone. Matthew Stafford was sacked five times and finished with 216 yards passing on 19 completions. He didn’t throw any touchdowns. The running game was also ineffective, with only 53 yards on 20 attempts.
Los Angeles couldn’t convert on third down, going just 1-for-5. Demarcus Robinson led the Rams with 50 yards receiving, 42 of which came on one catch. Blake Corum was the leading rusher with 28 yards.
Allowing 231 rushing yards on 40 attempts, the Rams’ defense struggled to stop the run in their 41-10 loss to the Cardinals. They gave up 489 total yards and 12.3 yards per attempt in the passing game. Arizona completed 81% of their passes against the Rams, with 3 touchdowns and 258 yards through the air.
On third downs, the Rams allowed the Cardinals to convert 63.6% of their chances. Los Angeles managed just one sack and lost the tackles for loss battle by a margin of -6.
San Francisco 49ers vs. Los Angeles Rams NFL Football Betting Trends
- The 49ers are 1-4 in their last five games as a favorite.
- Conversely, the Rams are 3-2 ATS in their last five games as an underdog.
- Also, the 49ers are 5-4-1 ATS in their last ten road games.
- On the other side, the Rams have gone 5-5 across their last ten home games.
- Over the 49ers’ last 3 road games, the over/under record is 0-2-1.
- The Rams’ have an over/under record of 1-2 in their last 3 games at home.
49ers vs. Rams Line Movement
| Open-ML | Live-ML | Open-Spread | Live-Spread | |
|---|---|---|---|---|
| 49ers | -225 | -349 | -5.5 | -7 |
| Rams | +185 | +276 | +5.5 | +7 |
4* Free Week 3 NFL Betting Prediction: 49ers -7
It’s a battle of the walking wounded, but don’t let that scare you away from the action—this game is dripping with betting intrigue!
Brock Purdy, Brandon Aiyuk, and George Kittle will have to step up big for San Francisco. The pressure is cranked up, and you know head coach Kyle Shanahan wants to keep his dominance over Sean McVay alive.
At -7, the 49ers are the safe bet on paper, but there’s always value in a desperate home underdog.
Our model has the 49ers coming out on top by a score of 24-16 in their week three matchup against the Rams. With the point spread sitting at -7 in favor of the Niners, we are locking in our pick on them to cover as road favorites.
As for the best way to attack the over/under, we like the OVER, with a projected combined score of 50 points and the O/U line sitting at 43.5 points.
Get your popcorn ready and your bets in because this matchup is set to be a hard-hitting, nail-biting clash!
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San Francisco 49ers vs. Los Angeles Rams NFL Betting Tweet Of The Day
Working 9️⃣ to 5️⃣ pic.twitter.com/iJaXB7ARXK
— Los Angeles Rams (@RamsNFL) September 20, 2024
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