
Free NFL Week 12 Pick: 49ers vs. Packers Odds
Looking for San Francisco 49ers vs. Green Bay Packers free NFL picks & NFL odds? NFL betting sees the 49ers taking on the Packers on Sunday, November 24th at the Lambeau Field. Cappers Picks provides complimentary NFL Football handicapping picks all NFL season long including all NFL Week 12 games so stay tuned for more FREE NFL predictions like this San Francisco Green Bay matchup.
NFL Handicapping Analysis: Week 12
(5-5) San Francisco 49ers vs. Green Bay Packers (7-3)
Date: Sunday, November 24th
Time: 4:25 ET
Venue: Lambeau Field, Green Bay WI
NFL ATS Betting Lines: (BET NOW!) San Francisco +2.5 | Green Bay -2.5
NFL Moneyline Odds: San Francisco +116 | Green Bay -138
NFL Betting Total: O/U 48
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The storied rivalry between the Green Bay Packers and San Francisco 49ers is set to add another thrilling chapter in Week 12 as these two iconic franchises square off at Lambeau Field.
With Green Bay holding a slight edge in the all-time series at 38-34-1, including a rich postseason history, the stakes are high as both teams push for playoff positioning.
Their last meeting was a nail-biter, with San Francisco edging out a 24-21 victory in January 2024. Now, Green Bay, sitting at 7-3, and San Francisco, battling at 5-5, are both desperate for a win to solidify their paths toward the postseason.
From a betting standpoint, there’s plenty to unpack. Green Bay enters as a slight favorite at -2.5, while the 49ers sit at +2.5 in a game that looks like a coin flip. The total is set at 48, but all signs point to the UNDER as the best value play.
Over the last three times playing each other, the 49ers have a record of 2-1. However, against the spread the Packers went 2-1. The over/under record in these matchups was 1-2 on an average of 41 points per game.
San Francisco 49ers
After back-to-back wins, the 49ers couldn’t keep the momentum going in week 11, falling 20-17 to the Seahawks at home. San Francisco was a 6-point favorite in this one, but the loss dropped them to 5-5 on the season. They are now 4th in the NFC West with a 1-3 division record and rank 10th in the conference.
Heading into week 12, the 49ers have a 26.8% chance of making the playoffs and an 18.8% chance of winning the division. Despite their .500 record, they rank 7th in our NFL power rankings. San Francisco has a +2.8 scoring margin this season and is 4-6 against the spread, having been favored in all of their games so far.
San Francisco 49ers Stats
Heading into week 12, the 49ers rank 10th in our offensive power rankings. They are 8th in the NFL, scoring 25 points per game, and 2nd in total yards, averaging 398.9 per game. San Francisco is 19th in passing attempts but 4th in passing yards, with 251.1 per game. They also rank 7th in rushing attempts and rushing yards, averaging 147.8 per game.
In week 11, Brock Purdy threw for 159 yards, completing 21 of 28 passes with one touchdown and one interception. Jauan Jennings led the team with 10 catches for 91 yards, while Christian McCaffrey rushed for 79 yards on 19 carries. The 49ers converted 7 of 11 third downs and scored on 2 of 3 red zone trips against the Seahawks.
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In their 20-17 loss to the Seahawks, the 49ers’ defense allowed just 195 passing yards on 25 completions. They also picked off one pass and pressured the quarterback with four sacks. Despite their efforts, Seattle still managed to convert 46.2% of their third down attempts. The 49ers’ run defense allowed 94 yards on 23 attempts.
Green Bay Packers
Heading into week 12 with a 7-3 record, the Packers have an 88.2% chance of making the playoffs, according to our projections. They rank 5th in our NFL power rankings, but their division record (1-2) has them 3rd in the NFC North. Green Bay has been better on the road (4-1) than at home (3-2) this season.
Against the spread, the Packers are 4-6 and have failed to cover in four straight games. In week 11, they were 6-point favorites against the Bears but only won by one. Their O/U record is 4-5-1, with the under hitting in two consecutive games.
Green Bay Packers Stats
Heading into week 12, the Packers are 12th in our offensive power rankings. They are 8th in the NFL in points per game (25) and 4th in yards per game (387.6). Despite being 21st in passing attempts, they rank 8th in passing yards per game with 237.7. On the ground, they are 6th in rushing attempts and 4th in rushing yards per game, averaging 149.9.
Jordan Love threw for 261 yards (13/17) and a touchdown in week 11 against the Bears, posting a passer rating of 112. Christian Watson led the team with 4 catches for 150 yards. Josh Jacobs had 76 yards and a touchdown on 18 carries. Green Bay struggled on 3rd down, converting just 1 of 5 attempts, but scored on 3 of 5 red zone trips.
Despite giving up 179 rushing yards on 34 attempts, the Packers’ defense held the Bears to 19 points in their 20-19 win. Chicago had a big day on the ground, averaging 5.3 yards per attempt. Green Bay’s run defense struggled, but they did manage to limit the Bears to 212 passing yards and allowed just 23 completions.
The Packers’ defense recorded three sacks and held Chicago to a 56.2% third-down conversion rate. Even though the Bears had some success running the ball, the Packers’ defense did enough to help secure the narrow victory.
San Francisco 49ers vs. Green Bay Packers NFL Football Betting Trends
- The 49ers are 3-2 in their last five games as an underdog.
- Conversely, the Packers are 2-3 ATS in their last five games as a favorite.
- Also, the 49ers are 6-4 ATS in their last ten road games.
- On the other side, the Packers have gone 5-5 across their last ten home games.
- Over the 49ers’ last 3 road games, the over/under record is 2-1.
- The Packers’ have an over/under record of 1-2 in their last 3 games at home.
49ers vs. Packers Line Movement
| Open-ML | Live-ML | Open-Spread | Live-Spread | |
|---|---|---|---|---|
| 49ers | -130 | +116 | -2.5 | +2.5 |
| Packers | +110 | -138 | +2.5 | -2.5 |
4* Free Week 12 NFL Betting Prediction: San Francisco +2.5
These teams have hit the UNDER in three of their last four matchups, and the trend holds strong in recent weeks—San Francisco has gone UNDER in five of their last six November games, while Green Bay has seen the UNDER hit in four of their last six at Lambeau.
Our projected score for this week 12 matchup between the 49ers and Packers is 23-20 in favor of the 49ers. With the point spread sitting at -2.5 in favor of the Packers, we like the Niners to not only win but cover as road underdogs.
For an over/under pick, we are leaning towards taking the under, with a projected combined score of 41 points and the O/U line at 48.
The 49ers are 6-4 ATS in their last ten road games, making them a tempting option against the spread, but this game screams defensive battle rather than a shootout.
Whether you’re tuning in for the rich history, the playoff implications, or the betting action, this matchup has all the makings of a classic November clash. Expect grit, drama, and plenty of tension as these NFC heavyweights go head-to-head in the frozen tundra.
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San Francisco 49ers vs. Green Bay Packers NFL Betting Tweet Of The Day
“You better stay resilient, you better keep fighting.” pic.twitter.com/pTOfhEcL1J
— Green Bay Packers (@packers) November 21, 2024
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