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Free Picks NFL Football Arizona Cardinals vs. San Francisco 49ers – 9/13/2020 Free Pick & NFL Betting Prediction

Arizona Cardinals vs. San Francisco 49ers – 9/13/2020 Free Pick & NFL Betting Prediction

September 7, 2020 by Matthew Lowrimore

Arizona Cardinals vs. San Francisco 49ers - 9/13/2020 Free Pick & NFL Betting Prediction

Free Week 1 Prediction: Cardinals vs. 49ers NFL Odds

Looking for Arizona Cardinals vs. San Francisco 49ers free NFL Week 1 picks & NFL odds? NFL betting sees the Cardinals taking on the 49ers on Sunday, September 13, 2020, at Levi’s Stadium in Santa Clara, California. Cappers Picks provides complimentary handicapping picks all NFL season long including all NFL Week 1 games so stay tuned for more FREE NFL predictions like this Arizona San Francisco matchup.

NFL Handicapping: Week 1

(0-0) Arizona Cardinals vs. San Francisco 49ers (0-0)
Date: Sunday, September 13
Time: 4:25 PM
Venue: Levi’s Stadium, Santa Clara, CA.
NFL Week 1 ATS Betting Lines: San Francisco -7
NFL Week 1 Moneyline Odds: Arizona +250 / San Francisco -310
NFL Week 1 NFL Betting Total: 47.5

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The runners-up in the Super Bowl last season will try to avoid the hangover as they open their season with a hungry divisional rival.

The 49ers cannot afford a slow start to the season because Arizona is looking to light them up after having acquired DeAndre Hopkins over the off-season.

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The Cardinals were 5-10-1 in Kyler Murray’s rookie season, but there is reason to believe they can improve in his sophomore season. On the other side, the 49ers have to pick up the pieces after blowing the Super Bowl and try to start this season off the right way.

Arizona Cardinals

The Cardinals while bad, had a decent offense in 2019. Though only ranking 17th in scoring, they averaged 22.6 points per game. Their passing offense was a little lacking, averaging just 217.3 yards per game.

The addition of DeAndre Hopkins is sure to help this area of their offense.

Not sure how their running game will fare however as they lost David Johnson. Kenyan Drake led their team in rushing last season, picking up 643 yards and 8 touchdowns. As a team, they ranked 10th in rushing, averaging 124.4 yards per game.

Their defense is really going to need to be the area that improves, considering they allowed 27.6 points per game and ranked 28th in the league. Especially against the pass, they allowed 281.9 yards per game.

Against the run, they allowed 120.1 yards per game and ranked 24th.

San Francisco 49ers

The 49ers were so close to glory and then it all ended within a few minutes. Teams in the past who have let a Super Bowl slip away tend to perform poorly the season after. Now there is a pandemic going on, so maybe that took the Super Bowl off the minds of the players and they can just go out and do their thing.

San Francisco will look to continue their balanced offense like they had last year, averaging 29.9 points per game and ranking 2nd in the NFL. They averaged 144.1 yards on the ground, also ranking second in the league.



The defense for the 49ers was also very good in 2019. They allowed 19.4 points per game, ranking eight in the league. They allowed 281.8 yards per game, 169.2 yards through the air and 112.6 yards per game on the ground.

With a pass happy offense like the Arizona Cardinals, it is possible that 49ers will focus too much on stopping Kyler Murray and they will allow some chunk plays on the ground.

NFL Betting Trends:

  • ARI are 7-3-2 ATS in their last 12 games overall.
  • Road team is 5-2-1 ATS in their last 8 meetings.
  • Over is 8-2-1 in SF last 11 vs. NFC.
  • Over is 7-2-1 in SF last 10 games as a favorite.
  • Over is 6-2 in ARI last 8 games on grass

4* Free NFL Betting Prediction: Arizona Cardinals +7

I really believe that the Super Bowl hangover is going to play a factor here for the 49ers. These teams also usually play close games being rivals, so I will back the Cardinals to cover here.

NFL Free Week 1 Score Prediction: Arizona 24 – San Francisco 28 (Bet Now!)

If you’re looking for more NFL picks like this Arizona Cardinals vs. San Francisco 49ers matchup we’ll be providing 4* free NFL predictions on the blog all season long, and check out our Experts for guaranteed premium & free NFL Football picks!

CappersPicks.com has NFL odds up on a ton of futures, and you will also find 2020 NFL lines up for weekly games as well.

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About Matthew Lowrimore

Matthew is new to Cappers Picks but has now been a freelance handicapper for over a year. He enjoys writing about all sports, but his passion is writing about College Football. Matthew uses different methods to back his predictions, such as statistics, key injuries and weather patterns. He also looks for odds & trends to help support his picks.

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Filed Under: NFL Football

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