– Last Updated on November 21, 2022 2:51 pm
NFL Week 5 Odds + Predictions
Week 5 of the NFL season is upon us and once again Vegas has been swift to establish the odds for every game on the schedule this weekend.
As per usual there are some barn-burners on the docket, some obvious mismatches and some games you just have to give the “ho-hum” to. If there is one thing we have learned however it is that there is no sure-thing in the NFL.
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Let’s take a look at the teams that ARE in action this week, the early lines for each of those games and what should play out on what promises to be another incredible week of NFL football.
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NFL Week 5 Odds for Week 4 NFL Action
With that in mind, let’s take a look at every game this weekend, the odds that accompany those games and what should play out.
Cardinals at 49ers (Opening line: Cardinals, -4 points)
Palmer is OUT. Some lines already have the Cards as 1.5 point favorites.
Drew Stanton is the next man up – he went 5-3 for the Cards in 2014 and has to be just OK against San Francisco. The 49ers have been surprisingly tough so far but lost defensive Stud Navarro Bowman on Sunday. Arizona HAS to win this game – I think they do easily.
Texans at Vikings (Opening line: Vikings, -6 points)
The Vikings have won all three meetings between the teams so far – not much of a reason to think differently about the outcome of this Sunday’s game – the Vikes are absolutely on fire. Houston has proven to be a poor road team and has had its struggles with NFC teams.
I like Minnesota to keep the roll going by a touchdown on Sunday – they are that good!
Titans at Dolphins (Opening line: Dolphins, -4)
Ugh – I won’t be recording this game to watch later! A battle of 1-3 teams isn’t exactly must-see! Miami isn’t as bad as they are playing right now and get the honor of facing a Titans team that is 5-13 ATS in their last 18 as road underdog.
Miami’s defense has been as bad as the offense – my guess is that any slight improvement will be enough against Tennessee this week.
Patriots at Browns (Opening line: Patriots, -7)
Expect the Pats to be favored by double digits by game-time here. Tom Brady is back baby and ready to destroy anyone in his way. I think New England does just that. After all the team was playing pretty well in his absence before last week.
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New England hasn’t lost many times the last few years but they are absolute money in games that follow. Looks for Brady and the boys to score early and to keep the foot on the pedal in an absolute romp in Ohio.
Jets at Steelers (Opening line: Steelers, -6 points)
The Jets haven’t been great at all – Ryan Fitzpatrick has thrown nine Interceptions in his last two games – nine! How the Jets face arguably the most prolific offense in the game – a team that did whatever it wanted against the Chiefs – a team that beat New York in Week 3.
Full of confidence I am expecting the Steelers to roll once again on Sunday. Don’t worry about the big spread here!
Redskins at Ravens (Opening line: Ravens, -4)
The Skins make their first trip to DC since 2008 – they haven’t been all that impressive on the road the last couple of years – just 10-15 ATS. The Ravens on the other hand are just 1-5-1 ATS as home favorites in their last seven.
I’m picking the upset here – Washington is a better team than they have been playing and Baltimore isn’t as good as their 3-1 record suggests.
Eagles at Lions (Opening line: Lions, -2.5 points)
My guess is that the line here will be switched – the Eagles will be favored and rightfully so. Philadelphia looks like one of the more balanced teams in the league right now while the Lions have been dreadful and suffered some more injuries this past Sunday.
Simply put Detroit just isn’t that good – I’m taking the red-hot Eagles by 4.
Bears at Colts (Opening line: Colts, -5 points)
A pair of 1-3 teams do battle in Indy on Sunday. Neither team is especially attractive. The Colts O-line is a disaster and the Bears as a whole are pretty bad.
Indianapolis returns home after a disheartening loss to Jacksonville – they will be tired and they will be a seriously disappointed group. I don’t love the Bears but I think they are better than Indy here. Take the upset!
Falcons at Broncos (Opening line: Broncos, -7)
It’s offense versus defense on Sunday when the scorching Falcons take on the Broncos who may be forced to start Paxton Lynch, who actually looked OK on Sunday.
The Broncos have won nine straight games heading into this weekend – as dominant a team as there is in the sport right now.
My guess is that the line drops a bit and that Denver is favored by about 4-4.5 by game time with Lynch – in that case I have to take Denver at home. Atlanta’s offense is scorching but they haven’t met anything like the Broncos defense yet!
Bills at Rams (Opening line: Rams, -1.5 points)
THE most surprising team in the NFL the LA Rams try to continue the momentum Sunday when they host a decent Buffalo team full of confidence after beating down the Patriots on the road last week. It all has to come crashing down for the Rams at some point – doesn’t it?
My guess is that they are humbled this week against a Bills team that is 9-5-1 ATS in their last 15 games as road underdog.
Chargers at Raiders (Opening line: Raiders, -3.5 points)
The line may move up here – it wouldn’t shock me to see the Raiders favored by 5.
If that happens I’m taking the Chargers, who, although losing on the scoreboard are keeping games very close! The Chargers are due for a little karma correction – against a Raiders team that is 0-3 ATS as home favorite and 6-10 ATS in their last 16 at home overall is a good spot for such a correction.
Bengals at Cowboys (Opening line: Bengals, -1 point)
This game figured to be a pick’em. In that case I am going with the Bengals – they have one of the most unstoppable weapons in the game right now in AJ Green and they could get Tyler Eifert back this week for his season debut.
The Bengals are 14-4-1 SU in their last 19 against NFC teams and 13-4-3 ATS in their last 20. To me, Cincinnati is simply the better team here!
Giants at Packers (Opening line: Packers, -6.5 points)
The Packers, off a bye, at home, on Sunday night. What’s not to love? How about their pass defense that has been absolutely shredded so far? Odell, Beckham, Victor Cruz and company should feast here and at very least keep this game close.
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I still like Green Bay to win, but by seven? It’s more like a 3-4 point game to me.
Buccaneers at Panthers (Opening line: Panthers, -6 points)
The status of Cam Newton is still unknown after his concussion in Week 5. But either way the Panthers are a desperate team that absolutely NEED a big performance on both sides of the ball.
My guess is that Cam plays and that the Bucs are exposed once again as one of the worst teams in the NFL. Take Carolina by a touchdown here!
Bye weeks: Chiefs, Saints, Seahawks, Jaguars
NFL Week 5 Handicapping
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CappersPicks.com has NFL odds up on a ton of futures, and you will also find 2016 NFL lines up for early games as well.