Free NFL Pick: Jaguars vs. Cardinals Odds
Looking for Jacksonville Jaguars vs. Arizona Cardinals Free NFL predictions? NFL betting sees the Jaguars taking on the Cardinals on 11/23 at State Farm Stadium, in Arizona. Cappers Picks provides complimentary expert handicapping picks on all NFL football matchups all season long so stay tuned for more FREE daily NFL predictions like this Jaguars Cardinals free pick.
2025 NFL Handicapping – Jacksonville Jaguars vs Arizona Cardinals
(6-4) Jacksonville Jaguars vs. Arizona Cardinals (3-7)
Date: Nov 23, 2025
Time: 4:05 PM ET
Venue: State Farm Stadium in Glendale, AZ
NFL Moneyline Odds: Jaguars -156 | Cardinals +131 (Bet Now!)
Today’s NFL Betting Odds: Jaguars -3.0 | Cardinals +3.0
NFL Football Gambling Total: O/U: 47.5
Here’s why I’m backing an OVER bet below in my Jaguars Cardinals free pick & gambling prediction for this matchup.
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Jaguars vs. Cardinals Gameday
The Jacksonville Jaguars head to State Farm Stadium for a showdown with the Arizona Cardinals. Jacksonville currently holds a 6-4 record, showing a balanced performance both at home and on the road. With Liam Coen as their head coach, the Jaguars aim to extend their form following a dominant victory over the Los Angeles Chargers.
The Arizona Cardinals face a challenging season but are looking to build on their recent passing performance with Jacoby Brissett leading the offense.
The Cardinals hold a 3-7 record and have struggled at home, with a 0-5 record at State Farm Stadium. Despite their struggles, players like Jacoby Brissett and Tyjae Spears have shown glimpses of skill. Arizona will need to capitalize on its strengths to compete against the Jaguars.
Historically, the Cardinals have had an upper hand in past matchups against the Jaguars. Their most recent encounter in 2017 saw Arizona secure a narrow 27-24 win at State Farm Stadium. The Jaguars, however, seek to rewrite history and turn the tide in this upcoming game.
As the game unfolds, weather conditions remain mild with overcast clouds, although the retractable roof at the stadium can mitigate any weather-related disruptions. With CBS broadcasting the event, fans eagerly await to see which team will capitalize on this critical matchup.
Week 12, Jacksonville Jaguars vs. Arizona Cardinals, we’re all hoping a great game is in store.
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Jacksonville Jaguars vs. Arizona Cardinals Odds & Last 5
The Jaguars are slightly favored with a moneyline of -157, while the Cardinals stand at +131. The spread leans towards Jacksonville by 3 points, indicating a close contest. The total is set at 47.5, suggesting potential high scoring.
Looking back at their recent performances, the Jaguars secured a dominant win over the Chargers with a 35-6 score. Yet, they faced setbacks against the Texans and Rams, indicating some inconsistency. Jacksonville will need to carry that strong form into this game.
The Cardinals, on the other hand, have shown flashes of offensive promise, including a standout passing performance against the 49ers. However, they have struggled defensively, allowing significant yardage and points.
Reflecting on past encounters, Arizona’s advantage is clear, having won the last three meetings since 2013. However, Jacksonville’s current form could challenge this trend.
The Jaguars aim to leverage their recent success and alter the historical narrative against the Cardinals.
Cardinals Stats
The Arizona Cardinals’ offensive stats for the 2024 season show a team struggling to put up consistent points. They scored 400 points, ranking 12th, with a passing yard total of 3,639, placing them 18th.
Their rushing attack ranked 7th with 2,451 yards, and they secured 356 first downs, ranking 8th in the league.
On defense, the Cardinals allowed 379 points, which placed them 14th. They recorded 41 sacks, ranking 8th, and managed 9 interceptions, ranking 11th. Additionally, they recovered 8 fumbles, placing them 7th, but allowed 5,823 opponent offensive yards, which was 21st in the league.
Recently, the Cardinals have struggled, losing their last two games to the 49ers and Seahawks. Despite a strong passing performance against the 49ers with 452 yards, turnovers were an issue with 2 interceptions and a fumble. Prior to these losses, they secured a win against the Dallas Cowboys, showing their potential to compete when both offense and defense perform well.
The team faces significant challenges due to injuries, with key players like Kyler Murray and Marvin Harrison Jr. out. Jacoby Brissett, the current starting quarterback, has thrown for 1,570 yards and 10 touchdowns in 7 games.
Bam Knight has contributed with 181 rushing yards and 3 touchdowns, but the team will need to rely on their depth to overcome these absences.
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Jaguars Stats
The Jaguars enter Week 12 with a mix of results. They secured a 35-6 win against the Los Angeles Chargers, showcasing a strong offensive display with 192 rushing yards. However, prior to that, they faced a setback against the Houston Texans in Week 10, losing 36-29.
Looking at the season stats, the Jaguars’ offense ranks 24th in both scoring and passing yards, with 320 points and 3,477 passing yards from the previous season. Their rushing game isn’t far behind, ranking 25th with 1,729 yards.
Defensively, the Jaguars have struggled, ranking 31st in opponent offensive yards with 6,629 yards allowed. However, they have been effective in creating turnovers, ranking 13th in interceptions and 11th in fumbles recovered. The defense will need to step up to contain the Cardinals’ offense.
Key players to watch include Trevor Lawrence, who leads the team with 2,151 passing yards and 11 touchdowns this season. Additionally, Travis Etienne Jr. has been a standout in the rushing game, accumulating 729 yards and 5 touchdowns.
The Jaguars will aim to maintain their offensive momentum from their recent win.
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Jaguars vs. Cardinals QB Matchup
Jacoby Brissett leads the Arizona Cardinals with steady play this season. He averages 224.3 passing yards per game and has thrown for 10 touchdowns over seven games, showcasing his ability to find the end zone. Brissett has kept turnovers in check with only three interceptions this season.
Brissett’s performance has been consistent, ranking 25th in passing yards among quarterbacks. His ability to manage the game and protect the football has been key for the Cardinals. As the Cardinals prepare to host the Jaguars, Brissett’s leadership will be crucial for their success.
On the other side, Trevor Lawrence commands the Jacksonville Jaguars’ offense. He averages 215.1 passing yards per game and has thrown 11 touchdowns over 10 games. Lawrence’s decision-making has been effective, with only eight interceptions this season.
Lawrence ranks 14th in passing yards among quarterbacks, showcasing his ability to move the ball down the field. As the Jaguars head to Arizona, Lawrence’s poise under pressure will be essential in navigating the Cardinals’ defense.
His dual-threat capability, with 18.1 rushing yards per game, adds another layer to his offensive arsenal.
Jacksonville Jaguars vs. Arizona Cardinals bottom line: The Jaguars’ recent form and offensive strength should give them the upper hand, but the Cardinals’ passing attack could keep things competitive.
Jacksonville Jaguars vs. Arizona Cardinals Football Betting Trends
- Jaguars have a 3-0 record straight-up as favorites in their last three regular season games.
- Jaguars have a perfect 5-0 over/under record in their last five away games.
- Jaguars have gone over the total in six of their last seven games after a win.
- Also, the Cardinals have hit the over in seven of their last eight home games.
- Additionally, the Cardinals have a 4-1 over/under record as underdogs in their last five games.
- Cardinals have a 5-1 over/under record in their last six games overall.
Jaguars Cardinals Free Pick: Over 47.5
Here is my Jaguars Cardinals free pick. Jacksonville have consistently gone over the total in their recent games, especially after a win.
With a 5-0 over/under record in their last five away games, they’ve shown a clear preference for high-scoring contests on the road.
Their ability to put up points on the road makes them a strong candidate for another high-scoring game.
Meanwhile, Arizona have also been involved in high-scoring games, hitting the over in seven of their last eight home games. Their 4-1 over/under record as underdogs only further supports the idea that they are likely to contribute to a game with plenty of points.
The total has gone OVER in 5 of Jacksonville’s last 5 games on the road, reinforcing their trend of high-scoring affairs away from home. Likewise, the total has gone OVER in 5 of Arizona’s last 6 games, with the Cards showing no hesitation to engage in shootouts.
Plus, the total has gone OVER in 7 of Arizona’s last 8 games at home and in 4 of Jacksonville’s last 6 games played in November. These trends suggest both teams have been involved in games that exceed expected point totals.
Given these trends, coupled with the current total set at 47.5, the over appears to be the more likely outcome for this matchup.
My system pick is Over 47.5.
Today’s NFL Free Pick
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NFL Betting Tweet Of The Day
Sunday at home 🏡
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— Arizona Cardinals (@AZCardinals) November 20, 2025
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