Free NFL Pick: Packers vs. Cardinals Odds
Looking for Green Bay Packers vs. Arizona Cardinals Free NFL predictions? NFL betting sees the Packers taking on the Cardinals on 10/19 at State Farm Stadium, in Arizona. Cappers Picks provides complimentary expert handicapping picks on all NFL football matchups all season long so stay tuned for more FREE daily NFL predictions like this Packers Cardinals free pick.
2025 NFL Handicapping – Green Bay Packers vs Arizona Cardinals
(3-1) Green Bay Packers vs. Arizona Cardinals (2-4)
Date: Oct 19, 2025
Time: 4:25 PM ET
Venue: State Farm Stadium in Glendale, AZ
NFL Moneyline Odds: Packers -307 | Cardinals +250 (Bet Now!)
Today’s NFL Betting Odds: Packers -6.5 | Cardinals +6.5
NFL Football Gambling Total: O/U: 44.5
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Packers vs. Cardinals Gameday
The Green Bay Packers hit the desert with momentum and a purpose. Sitting at 3-1-1, Matt LaFleur’s team has looked sharp through six weeks, blending efficient quarterback play with a bruising run game.
Their 27-18 win over Cincinnati last week showed their balance — methodical drives, defensive stops, and just enough Jordan Love magic.
Meanwhile, the Arizona Cardinals are limping into this one at 2-4. Jonathan Gannon’s group continues to compete but can’t seem to close games, most recently falling 31-27 to the Colts.
Playing at home inside State Farm Stadium gives them a shot to reset, but they’ll need a near-perfect effort to keep pace with Green Bay’s offensive rhythm.
Historically, this matchup’s been streaky. The Packers handled the Cardinals comfortably in 2024, but Arizona’s had its moments in prior years. Both teams enter desperate to prove something — Green Bay wants to keep pace atop the NFC North, while the Cards are trying to stop a midseason slide.
The weather’s a non-factor under clear Arizona skies. Expect a fast-paced game, lots of motion, and plenty of points.
Week 7, Green Bay Packers vs. Arizona Cardinals — and yes, we’re all hoping this one delivers.
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Green Bay Packers vs. Arizona Cardinals Odds & Last 5
Oddsmakers like the visitors here, with Green Bay favored at -321 on the moneyline and laying -6.5 on the spread. Arizona sits at +258, hoping the desert air and home crowd can help them spring an upset.
The Packers come in fresh off that win over Cincinnati, their third victory in five games. Their only loss this season came on the road in Cleveland, a 13-10 heartbreaker.
Still, their offense looks increasingly confident behind Jordan Love and Josh Jacobs.
The Cardinals’ latest loss to Indianapolis was another “almost” — 31-27 in a shootout where the offense moved the ball but the defense couldn’t get a stop. The pattern’s become familiar: they hang around, they flash talent, but they can’t quite finish.
Against a veteran Packers team, that margin for error shrinks.
Cardinals Stats
The Cardinals’ recent skid isn’t for lack of effort — it’s depth, injuries, and closing. They’ve lost four straight but continue to show life on offense. Last week, Arizona put up 312 passing yards on the Colts, with backup Jacoby Brissett slinging for 320 yards and two scores.
Kyler Murray’s status remains a game-time decision due to a foot issue, which could again thrust Brissett into the spotlight. Murray’s thrown for 962 yards and six touchdowns in five games, adding 34 rushing yards per contest.
If he’s able to go, the Cardinals’ offense looks completely different.
The backfield’s thin, though. With James Conner out for the season and Trey Benson sidelined, Bam Knight and Michael Carter carry the load. The duo combined for just 61 rushing yards last week — a problem against a defense as physical as Green Bay’s.
In the air, Marvin Harrison Jr. and Trey McBride have been bright spots. McBride leads the team with 347 yards, while Harrison adds 338 — though his concussion status clouds his availability. If both sit, Arizona’s offensive ceiling drops sharply.
Defensively, the Cards continue to leak yards, particularly on the ground.
That’s bad news against Jonathan Taylor’s heir apparent, Josh Jacobs.
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Packers Stats
Green Bay’s offense has hit stride, ranking top 10 in total yardage and top five in rushing production dating back to last season.
They’ve piled up 2,496 rushing yards and 3,802 passing yards in that span, thanks to a line that bullies fronts and a quarterback who rarely blinks under pressure.
Defensively, the Packers are legit. They rank sixth in opponent points allowed (338 last year), with 45 sacks and 17 interceptions — both top-six in the NFL. That opportunistic edge showed up again last week when they picked off Joe Burrow twice and forced a fumble in the red zone.
Jordan Love has been steady, not flashy. His 1,259 passing yards and nine touchdowns come with just two interceptions. He’s making smart reads, protecting the ball, and delivering when it counts.
Running back Josh Jacobs remains the tone-setter — 93 yards and two touchdowns against the Bengals last week reminded everyone what he brings.
Injuries are piling up, though. Jayden Reed and rookie back MarShawn Lloyd are on IR, while a few linemen are banged up. Still, LaFleur’s offense has enough balance to keep humming.
The Packers’ combination of efficiency and defensive consistency has been the difference all year.
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Packers vs. Cardinals QB Matchup
If Kyler Murray plays, the Cardinals’ offense instantly becomes dynamic again. He’s averaging 192 passing yards, 35 rushing yards, and 1.2 total touchdowns per game.
When healthy, Murray’s ability to extend plays and create out of nothing gives Arizona a fighting chance.
If not, Jacoby Brissett steps back in after a 320-yard performance against Indy. He’s serviceable but lacks Murray’s explosiveness — and against Green Bay’s secondary, that difference could matter.
Jordan Love remains steady for the Packers. He’s averaging 252 passing yards and nearly two touchdowns per game with just two interceptions all season. His pocket awareness and accuracy have taken major leaps this year, and he’s spreading the ball to a deep rotation of receivers.
Projected stats put Love around 260 yards and two touchdowns, while Murray (if active) is pegged for roughly 215 yards and one score.
If Brissett starts, those numbers dip.
Either way, Green Bay’s offensive balance gives them the edge.
Green Bay Packers vs. Arizona Cardinals bottom line: The Packers have the better roster, steadier quarterback, and stronger defense — and they’re rolling.
Green Bay Packers vs. Arizona Cardinals Football Betting Trends
- The Packers are 9-3 against the spread as favorites in their last 12.
- In the last three games as an underdog, the Cardinals are 2-1 ATS.
- The Packers have gone over the total in two of their last three games as favorites.
- Also, the Cardinals have seen the total go over in five of their last six home games.
- The Packers are 4-2 against the spread after a loss in their last 6.
- Additionally, the Cardinals are 4-4 against the spread in their last eight home games.
Packers vs Cardinals Prediction: Over 44.5
Here is my Packers Cardinals free pick. The Green Bay Packers have been reliable for over bettors lately, going over the total in two of their last three games when listed as favorites.
Their offense continues to find rhythm, especially in games where they’re expected to control possession and dictate the scoring pace.
The Arizona Cardinals have also developed a clear over pattern at home, with the total going over in five of their last six games at State Farm Stadium. That trend reflects their ability to turn home games into shootouts, as their offense typically feeds off the fast indoor surface and crowd energy.
Both teams bring enough offensive firepower to stretch the field and push the pace early. The Packers’ efficient passing game combined with the Cardinals’ knack for trading scores sets up an ideal scenario for points to pile up quickly.
Given both teams’ strong over trends, the over 44.5 is the sharpest play in this matchup.
With Green Bay’s scoring consistency as favorites and Arizona’s high-scoring tendencies at home, this one has a high-total result in Glendale written all over it.
Today’s NFL Free Pick
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NFL Betting Tweet Of The Day
core mems
top ✋ plays against the Packers pic.twitter.com/DkbeaMDT6J
— Arizona Cardinals (@AZCardinals) October 15, 2025
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