Free NFL Pick: Broncos vs. Colts Odds
Looking for Denver Broncos vs. Indianapolis Colts Free NFL predictions? NFL betting sees the Broncos taking on the Colts on 9/14 at Lucas Oil Stadium, in Indianapolis. Cappers Picks provides complimentary expert handicapping picks on all NFL football matchups all season long so stay tuned for more FREE daily NFL predictions like this Broncos Colts free pick.
2025 NFL Handicapping – Denver Broncos vs Indianapolis Colts
(1-0) Denver Broncos vs. Indianapolis Colts (1-0)
Date: Sep 14, 2025
Time: 4:05 PM ET
Venue: Lucas Oil Stadium in Indianapolis, IN
NFL Moneyline Odds: Broncos -127 | Colts +107 (Bet Now!)
Today’s NFL Betting Odds: Broncos -2 | Colts +2
NFL Football Gambling Total: O/U: 42.5
- Live Betting Odds for today’s Broncos vs. Colts game!
- Want more football predictions like this Broncos Colts play? Check out our free NFL AI Picks for today!
- View our Updated Sportsbook Bonuses for today!
Broncos vs. Colts Gameday
As Week 2 unfolds, the Denver Broncos travel to face the Indianapolis Colts at Lucas Oil Stadium. Both teams enter this game with a 1-0 record, having begun their seasons on a high note. The Broncos’ last outing saw them secure a win against the Tennessee Titans, while the Colts overcame the Miami Dolphins.
Denver’s coaching staff, led by Sean Payton, orchestrated a solid performance in their opener. Their defense, managed by Vance Joseph, proved to be effective with players like Talanoa Hufanga and Ja’Quan McMillian stepping up. Meanwhile, offensive figures such as J.K. Dobbins and Courtland Sutton contributed significantly to their victory.
On the other hand, the Colts, with Shane Steichen at the helm, delivered an impressive show against Miami. The offense showed precision, highlighted by Daniel Jones and Michael Pittman Jr. On defense, Kenny Moore II and Nick Cross played key roles in limiting the Dolphins’ scoring opportunities.
Week 2, Denver Broncos vs. Indianapolis Colts, we’re all hoping a great game is in store.
Expert NFL Betting Picks
Looking for more NFL betting picks? Check out today’s featured premium plays from CappersPicks handicappers, including sides, totals, and weekly NFL betting packages.
Denver Broncos vs. Indianapolis Colts Odds & Last 5
Interestingly, the game odds highlight a narrow margin between the two teams. The Denver Broncos are slightly favored with a moneyline of -127, while the Indianapolis Colts have a moneyline of +107. The spread is set at -2.5 for Denver and +2.5 for Indianapolis, suggesting a tight contest is expected.
Looking back at their previous games, Denver’s victory over the Tennessee Titans featured a strong defensive showing. They allowed only 12 points and limited the Titans to just 62 passing yards. Meanwhile, the Colts displayed offensive dominance against the Miami Dolphins, racking up 262 passing yards to secure a comfortable win.
As both teams head into this clash at Lucas Oil Stadium, the game history shows Denver has had success in recent meetings. The Broncos won their last two encounters, including a preseason game at this venue. Yet, with both teams starting the season strong, this matchup could be a contest worth watching.
Colts Stats
Starting with the Colts’ recent performance, they kicked off the 2025 season with a decisive 33-8 win against the Miami Dolphins. Daniel Jones led the charge, completing 22 passes for 272 yards and a touchdown. This strong start sets a positive tone as they prepare for their next game against the Denver Broncos.
Looking at the offensive stats from last season, the Colts ranked 16th in scoring and 8th in rushing yards. Their passing game, however, struggled a bit, ranking 25th. They will aim to improve in this area to balance their offensive attack.
On defense, the Colts allowed 427 points, ranking 23rd in the league. Despite this, they excelled in forcing turnovers, ranking 4th in interceptions and 5th in fumbles recovered. Their ability to create turnovers could be a key factor against the Broncos.
In terms of player performance, Jonathan Taylor stands out with 71 rushing yards in the opening game. Michael Pittman Jr. also made an impact, catching six passes for 80 yards and a touchdown. These players will be crucial in maintaining offensive momentum.
As for injuries, the Colts have several key players on the injured reserve list, including D.J. Montgomery and Salvon Ahmed. Tyler Goodson and Jaylon Jones are listed as day-to-day, which could affect their depth. The Colts will need to adjust and rely on their depth to fill these gaps.
Looking ahead to their matchup with the Broncos, the Colts will play at Lucas Oil Stadium under scattered clouds with a warm breeze. The retractable roof should ensure optimal playing conditions. With a strong start to the season, the Colts aim to continue their winning ways in Week 2.
YOU CAN CLICK HERE TO CHECK OUT OUR TOP NFL CAPPERS! (All Under 1 Roof)
Broncos Stats
First, let’s delve into the Denver Broncos’ recent performance. In Week 1, they secured a 20-12 win against the Tennessee Titans at home. The Broncos displayed a strong defensive effort, limiting the Titans to just 12 points and only 62 passing yards.
Offensively, the Broncos showed balance with 166 passing yards and 151 rushing yards. Bo Nix led the charge with 176 passing yards, one touchdown, and two interceptions. Meanwhile, J.K. Dobbins contributed significantly on the ground with 63 rushing yards and a touchdown.
Transitioning to the Broncos’ season stats from last year, they ranked 10th in scoring with 425 points. Their passing game was middle-of-the-pack, ranking 20th with 3,610 yards. However, their defense was a standout, ranking 3rd in opponent scoring and 1st in sacks with 63.
Now, focusing on individual performances, Courtland Sutton was a key player in Week 1 with six receptions for 61 yards and a touchdown. On the defensive side, Talanoa Hufanga led with seven solo tackles. Ja’Quan McMillian and Zach Allen also recorded a sack each.
Looking ahead to their matchup against the Colts, Bo Nix is projected to throw for 228.6 yards and 1.6 touchdowns. J.K. Dobbins is expected to rush for 61.2 yards and add 0.5 touchdowns. These projections suggest a continued balanced attack from the Broncos.
Finally, the Broncos face some injury concerns, with Michael Burton and Malcolm Roach out for the season. Evan Engram and Dre Greenlaw are day-to-day with calf and quad issues, respectively. These injuries could impact the Broncos’ depth as they prepare for Week 2.
We want to hear from you below! Comments are welcome! Give us your picks for this Denver Broncos vs. Indianapolis Colts NFL matchup.
Broncos vs. Colts QB Matchup
Daniel Jones leads the Indianapolis Colts into Week 2 with a solid performance in the season opener. He threw for 272 yards and added 26 rushing yards, contributing to his one touchdown. His projected stats for this game include 225.2 passing yards and 1.4 touchdowns, indicating a consistent performance.
Jones’s ability to avoid interceptions is noteworthy, as he recorded none in the first game. With a fantasy point projection of 17.4, he remains a key player for the Colts. His connection with Michael Pittman Jr., who had 80 receiving yards, will be crucial in this matchup.
Bo Nix, the starting quarterback for the Denver Broncos, had a decent start to the season. He passed for 176 yards and rushed for 18 yards, also securing a touchdown. For this game, Nix is projected to throw for 228.6 yards and 1.6 touchdowns, showing potential for improvement.
Nix’s performance will be vital for the Broncos as they face the Colts. His fantasy point projection stands at 17.0, suggesting he can be a reliable option. The Broncos will look to capitalize on his connection with Courtland Sutton, who had 61 receiving yards in the opener.
Denver Broncos vs. Indianapolis Colts Football Betting Trends
- Denver is 0–1 against the spread in 2025.
- Indianapolis is 1–0 against the spread in 2025.
- Bo Nix is 12–7 ATS as a starting quarterback.
- Both teams’ Week 1 totals landed under the number.
- Denver has covered six of its last ten overall.
- Colts were 5–3 ATS at home last season; 1–0 at home now.
Broncos vs Colts Prediction: Under 42.5
The Broncos continue to lean on their defense, which ranked third in opponent scoring last season and regularly dictated the pace of games. Their ability to limit explosive plays should make life difficult for the Colts’ offense.
Indianapolis brings some defensive bite as well, finishing fourth in interceptions a year ago. That opportunistic approach could rattle Denver’s attack, but it also signals a stop-and-start type of game where long drives are tough to sustain.
Trends back the under too, with both teams sitting 0-1 on totals this season and consistently cashing unders over their last 10. Even their most recent head-to-head clash fell below 43.5, showing a history of low-scoring results when these squads meet.
All signs point toward another grind-it-out affair where defense dictates and points are at a premium.
With both teams carrying more strength on the defensive side of the ball, the posted number of 42.5 feels inflated. Expect another tight contest where scoring opportunities are limited and drives stall before reaching the end zone.
Given the stats, betting history, and matchups, the under 42.5 stands out as the sharpest play. Look for a defensive battle that stays well below the total.
Today’s NFL Free Pick
Best Sportsbooks For Denver Broncos vs. Indianapolis Colts NFL Gambling Today!
- 50% Reload Bonuses
- Daily Player Promos
- Live Dealer Casino
- Crypto Deposits
- Same-Game Parlays
- Casino + Poker
- Same-Game Parlays
- Overnight Lines
- Progressive Jackpots
- Reduced-Juice Lines
- 7% Racebook Rebate
- 100% Crypto Bonus
- VIP Cash Rewards
- Live Betting & Props
- High Betting Limits
NFL Betting Tweet Of The Day
the boss man in blue 💙 pic.twitter.com/dn8P4gmwbg
— Indianapolis Colts (@Colts) September 7, 2025
Also, if you’re looking for more NFL picks like this Denver Broncos vs. Indianapolis Colts 2025 Week 2 matchup we’ll be providing 4* free NFL predictions on the blog all season long. In fact, you can check out our Experts for guaranteed premium & free NFL Football picks!
Lastly, register here for a FREE NFL Football Betting Account Now for Daily Free Picks & More Special NFL Regular Season Offers!
