Cleveland Guardians vs. San Francisco Giants 6/17/2025 Free Pick & MLB Betting Prediction

Free MLB Pick: Guardians vs. Giants Odds

Looking for Cleveland Guardians vs. San Francisco Giants Free MLB predictions? MLB betting sees the Guardians taking on the Giants on Tuesday, June 17th, 2024 at Oracle Park, in San Francisco, CA. Cappers Picks provides complimentary expert handicapping picks on all MLB baseball matchups all season long so stay tuned for more FREE daily MLB predictions like this Guardians Giants free pick.

2025 MLB Handicapping – Cleveland Guardians vs San Francisco Giants

(35-35) Cleveland Guardians vs. San Francisco Giants (41-31)
Date: Tuesday, June 17th
Time: 9:45 ET
Venue: Oracle Park San Francisco, CA
Projected Starting Pitchers: Slade Cecconi vs. Robbie Ray
MLB Moneyline Odds: Guardians +139 | Giants -165 (Bet Now!)
Today’s MLB Run Line Betting Odds: Guardians +1.5 | Giants -1.5
MLB Baseball Gambling Total: O/U: 7

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Guardians vs. Giants Gameday

At 9:45 PM ET, the Guardians and Giants will square off in an interleague matchup. This one is being played at Oracle Park in San Francisco, and the Guardians are looking to snap a three-game losing streak vs. the Giants, who have won two straight.</

Overall, the Guardians are 35-35, while the Giants have the second-best record in the NL West at 41-31. San Francisco is the heavy favorite on the money line, with odds of -165 compared to the Guardians at +139. Tuesday’s forecast in San Francisco calls for clear skies and temperatures in the mid-70s. Robbie Ray is starting for the Giants, and the Guardians are going with Slade Cecconi.

Cleveland Guardians

Cleveland closed out their series vs. the Mariners with a 6-0 loss on the road. The Guardians were the slight underdog at +103 on the money line. Things really got away from the Guardians in the 2nd inning, as the Mariners scored five runs in the inning. Cleveland’s offense didn’t score their first run until the 5th.

Luis Ortiz got the start for the Guardians and took the loss. He only lasted six innings, giving up six earned runs on five hits. Ortiz also issued five walks and hit a batter. Cleveland’s offense scored their only run on a single by Bradley Zimmer in the
5th.

Cleveland will be looking to get back to .500 today, as they come in at 35-35 overall, having dropped three straight games. The Guardians lost the final three games of their series vs. the Mariners. In the AL Central, they are 9.5 games behind the Tigers.

So far, the Guardians have been good against other AL Central teams, putting up a record of 14-5. They have gone 16-20 on the road compared to 19-15 at home. As the underdog, Cleveland has an even 35-35 record and have dropped three straight as the underdog.

Guardians Stats

Heading into today’s game, the Guardians are averaging just 3.9 runs per game, which is 25th in the league. They are also near the bottom of the league in team batting average, on-base percentage, and OPS. One of the few bright spots in the lineup has been José Ramírez, who is batting .324 for the season and has a team-high 13 home runs. Carlos Santana is also having a solid season in terms of power, with eight homers, but he is batting just .248.

Over his last six games, Ramírez has gone 5/22 with one home run, and Carlos Santana has gone just 4/22. Bo Naylor is also struggling, going just 2/12 in his last five games. Nolan Jones is on a three-game hitting streak and has gone 4/14 in his last six games.

San Francisco Giants

The Giants will be looking to get back on track after closing out their series vs. the Dodgers with a 5-4 loss. This was especially tough, as they held a lead going into the 4th inning before the Dodgers scored three runs in the 4th to take the lead. San Francisco was the +155 underdog going into this road game.

Sean Hjelle got the start for the Giants and took the loss. He only lasted 3 2/3 innings, giving up two earned runs, and issued the walk. Daniel Johnson had a big game at the plate, going 1/1 with a homer and scoring run. The Giants also had three other players with two hits.

San Francisco is 41-31 overall and trail the Dodgers by 2.5 games in the NL West. The Giants lost the final two games of their series vs. the Dodgers. So far, they are 9-10 in divisional games.

At home, the Giants have gone 22-11 this year, and they are just above .500 at 19-20 on the road. As the underdog, the Giants have put together a matching 41-31 record. They come in having won five straight at home, and their overall series record is 13-8-2.

Giants Stats

San Francisco has been one of the better home run-hitting teams in the league this season, as they are 15th in the league in homers and have three players with at least 11 homers. This includes Matt Chapman, who is 12th in the league with 12 homers and is batting just .243 this season. Wilmer Flores and Heliot Ramos have also gone deep 11 times this season, with Flores leading the team with 51 RBIs.

Over his last eight games, Casey Schmitt has gone 7/23 with three homers, and Dominic Smith is also swinging a hot bat, going 9/26 with a homer in his last eight games. Mike Yastrzemski is currently on a six-game hitting streak for the Giants.

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Guardians Giants Pitching

Slade Cecconi and the Cleveland Guardians are on the road to take on the San Francisco Giants. Cecconi has started 3 games this season and has a win and 2 losses. He has gone 5 innings in each of his last 2 starts, giving up 2 earned runs to the Yankees and 1 earned run to the Reds.

Giants starter Robbie Ray comes into the game with a record of 8-1 and an ERA of 2.54. So far this season, he has made 14 starts, and opponents are batting .200 off the left-hander. Ray’s WHIP for the season is 1.12. Looking at his overall numbers, Ray has made nine quality starts and is averaging 10.18 strikeouts per nine innings. In his last outing, Ray finished with a no-decision, giving up two earned runs in four innings of work. Before that, he had won three straight starts.

Cleveland Guardians vs. San Francisco Giants MLB Baseball Betting Trends

• The Guardians head into the game having gone 4-6 straight-up in their last ten games on the road.
• The Guardians they are 6-4 vs. the runline in their previous ten games on the road.
• Conversely, the Giants are 5-5 over their last ten home games (straight-up).
• Furthermore, the Giants have a 5-5 mark vs. the runline across their last ten home games.
• Also, the Guardians are 1-2 in their last three games as the favorite. On the other hand, they are 1-2 as the underdog (last 3).
• The Giants have a record of 2-1 across their last three games when favored. As the underdog, they are 1-2 in their last three games.

Guardians vs. Giants Prediction: Guardians ML +139

We see the Guardians taking this one on the road against the Giants with a final score prediction of 5-4. Given that the Guardians are the underdogs, we recommend taking them on the money line, where they are currently at +139.

Looking at the starting pitchers, Robbie Ray is projected to have a solid outing, and if you’re looking for a parlay option, you could pair a Giants win with Ray picking up the win. However, we are sticking with the Guardians to win this one outright.

Today’s MLB Free Pick

MLB Betting Tweet Of The Day

F.P. Santangelo sat down with Dusty Baker, and many baseball stories were shared 🎤

💻 https://t.co/0Tv1u8GCoV pic.twitter.com/APv4tT17Vt

— SFGiants (@SFGiants) June 17, 2025

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About Matthew Wiesenfeld

For nearly a two decades the Wiesguy has been helping readers learn and win. Hailing from Toronto, Canada he is a true expert. He is always a little sweet on the underdogs while covering all sports to give you the insight you need to build your bankroll.

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