Free MLB Pick: Guardians vs. Twins Odds
Looking for Cleveland Guardians vs. Minnesota Twins Free MLB predictions? MLB betting sees the Guardians taking on the Twins on Wednesday, May 21st, 2024 at Target Field, in Minnesota, MN. Cappers Picks provides complimentary expert handicapping picks on all MLB baseball matchups all season long so stay tuned for more FREE daily MLB predictions like this Guardians Twins free pick.
2025 MLB Handicapping – Cleveland Guardians vs Minnesota Twins
(25-21) Cleveland Guardians vs. Minnesota Twins (26-21)
Date: Wednesday, May 21st
Time: 1:10 ET
Venue: Target Field Minneapolis, MN
Projected Starting Pitchers: Gavin Williams vs. Chris Paddack
MLB Moneyline Odds: Guardians -101 | Twins -118 (Bet Now!)
Today’s MLB Run Line Betting Odds: Guardians -1.5 | Twins +1.5
MLB Baseball Gambling Total: O/U: 7.5
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Guardians vs. Twins Gameday
Wednesday’s matchup between the Guardians and Twins is set to get started at 1:10 PM ET from Target Field in Minneapolis. The Twins are 2nd in the AL Central, while the Guardians are 3rd, with both teams having a record of 26-21.
Cleveland comes into the game as the slight money line favorite, with their odds sitting at -101, while the money line odds for the Twins are at -118.
The over/under line is currently at 7.5 runs, and the forecast for Wednesday’s game in Minneapolis calls for light rain and temperatures in the mid 40s. MLBN will be carrying this game on TV, and Gavin Williams is starting for the Guardians, while the Twins are going with Chris Paddack.
Cleveland Guardians
The Guardians wrapped up their series vs. the Reds with a 3-1 loss on the road. Cleveland was the +112 underdog going into this matchup. Things started off well for the Guardians, as they got on the board with a run in the 1st inning but gave up the lead right away as the Reds scored twice in the bottom of the first.
Luis L. Ortiz got the start for the Guardians and took the loss. He only lasted five innings, giving up two earned runs on six hits. Carlos Santana went 2/4 with a run scored and a walk.
Cleveland is on the road today vs. the Twins, having lost four straight games. Currently, the Guardians are 3rd in the AL Central, trailing the Tigers by 5.5 games. So far, they have been good against other AL Central teams, going 10-3.
At home, the Guardians have gone 14-8 this year and are just under .500 at 11-13 on the road. Cleveland has yet to play a game as the favorite this season, and they are 25-21 as the underdog. The team’s overall series record is 9-6 coming into today’s matchup.
Guardians Stats
Jose Ramirez has been on a tear of late for the Guardians, batting .346 over his last seven games with three homers and seven runs scored. Overall, he is batting .296 with nine homers and 23 RBIs. Kyle Manzardo leads the team with 10 homers but has a batting average of just .221. Manzardo also comes into the game on a five-game hitting streak.
As a team, the Guardians are averaging 4 runs per game, which is 22nd in the league. They have been a better offensive team on the road so far, averaging 4.4 runs per game. Overall, the Guardians are 11th in home runs but are batting just .233 as a team.
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Minnesota Twins
The Twins will be looking to get back on track after closing out their series vs. the Brewers with a 5-2 loss. This was especially tough, as it was the Twins’ third straight loss. Minnesota was the +120 underdog on the road going into this matchup.
Zebby Matthews got the start for the Twins and took the loss. He only lasted three innings, giving up four earned runs on five hits. Royce Lewis had a good game at thejson plate, going 1/4 with a homer.
Minnesota is 26-21 overall and trails the Tigers by five games in the AL Central. The Twins are 7-10 in the division but have won nine of their last ten games overall. At home, the Twins are 15-6 this season and have won nine straight at home as the underdog. So far, they have yet to be the favorite in a game.
As the underdog, the Twins have been good this season, putting together an overall series record of 9-6. They have also won five straight series overall, and three straight series on the road. Today, they host the Guardians, who are 5.5 games behind the Tigers and just a half-game behind the Twins.
Twins Stats
Minnesota’s offense is averaging 4.1 runs per game this season, which is 18th in the league. At home, they have been a bit better, averaging 4.7 runs per game. As a team, the Twins are batting .242, which is 15th in the league, and they are also near the middle of the pack in terms of home runs and slugging percentage. One area they have struggled in is drawing walks, as they are 23rd in the league in this category.
Center fielder Byron Buxton has been a bright spot for the Twins this season, as he is 8th in the league with 10 home runs and is also 14th in the league with 27 RBIs. Over his last 10 games, Trevor Larnach has gone 13/42 with three homers and seven RBIs. This has helped him move his season batting average up to .244.
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Guardians Twins Pitching
Cleveland is sending Gavin Williams to the mound today vs. the Twins, and he comes into the game with a record of 3-2 and an ERA of 4.29. Williams has made nine starts this year and has pitched much better at home, coming in with a record of 3-1 and an ERA of 5.25. On the road, his ERA is 5.21, and he has a record of 0-1. Williams’ WHIP for the season is 1.64, and he is coming off a start in which he gave up two earned runs in five innings of work. He finished with a no-decision in that outing.
Chris Paddack gets the start for the Twins today and comes into the game with a record of 2-3 and an ERA of 4.05. So far, he has made nine starts and two of them have been quality starts. Paddack’s WHIP for the season is currently 1.18, and opponents are batting .232 off the right-hander this year. In his last outing, he didn’t give up a run in seven innings of work, picking up the win. Before that, he had given up at least one homer in three straight outings. Paddack has been much better at home, coming in with an ERA of 3.34 compared to 6.66 on the road.
Cleveland Guardians vs. Minnesota Twins MLB Baseball Betting Trends
- The Guardians head into the game having gone 5-5 straight-up in their last ten games on the road.
- The Guardians they are 4-6 vs. the runline in their previous ten games on the road.
- Conversely, the Twins are 7-3 over their last ten home games (straight-up).
- Furthermore, the Twins have a 6-4 mark vs. the runline across their last ten home games.
- Also, the Guardians are 0-3 in their last three games as the favorite. On the other hand, they are 1-2 as the underdog (last 3).
- The Twins have a record of 3-0 across their last three games when favored. As the underdog, they are 2-1 in their last three games.
Guardians vs. Twins Prediction: Guardians ML -101
Our predicted final score for this Guardians vs. Twins matchup is 5-1 in favor of the Guardians. Given that the Guardians are the underdogs on the money line at -101, this is the way we would recommend playing this one.
If you’re looking for an over/under prediction, we like the under at 7.5 runs.
Looking at the starting pitchers, Gavin Williams is projected to finish with seven strikeouts compared to Chris Paddack at six.
Today’s MLB Free Pick
MLB Betting Tweet Of The Day
We saw all the good boys and girls at Target Field last night! 🥹🐾 pic.twitter.com/XNEX7TRzrP
— Minnesota Twins (@Twins) May 20, 2025
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