Free NFL Week 16 Pick: Cardinals vs. Panthers Odds
Looking for Arizona Cardinals vs. Carolina Panthers free NFL picks & NFL odds? NFL betting sees the Cardinals taking on the Panthers on Sunday, December 22nd at the Bank of America Stadium. Cappers Picks provides complimentary NFL Football handicapping picks all NFL season long including all NFL Week 16 games so stay tuned for more FREE NFL predictions like this Arizona Carolina matchup.
NFL Handicapping Analysis: Week 16
(7-7) Arizona Cardinals vs. Carolina Panthers (3-11)
Date: Sunday, December 22nd
Time: 1:00 ET
Venue: Bank of America Stadium, Charlotte NC
NFL ATS Betting Lines: (BET NOW!) Arizona -4 | Carolina +4
NFL Moneyline Odds: Arizona -207 | Carolina +171
NFL Betting Total: O/U 47
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The Week 16 clash between the Arizona Cardinals (7-7) and Carolina Panthers (3-11) brings plenty of intrigue for NFL fans and bettors alike.
Historically, the Panthers have dominated this matchup, holding a 14-6 all-time advantage, including a 2-1 edge in postseason battles.
While Arizona got the upper hand in their most recent meeting—a 26-16 win in Carolina back in 2022—the Panthers have historically been tough to beat at home, boasting a strong 8-4 record against the Cards in Charlotte.
When looking back over the last three times these two teams have played, the Panthers have the leg up at 2-1. The Panthers also had the edge vs. the spread in these games, at 2-1.
These games averaged a combined total of 46 points per game leading to an over/under record of 1-1-1.
Arizona enters as a 4-point favorite, but recent trends tell a compelling story for Carolina.
Arizona Cardinals
Arizona snapped a three-game losing streak in week 15, defeating the Patriots 30-17 to even their record at 7-7. The Cardinals were 6-point favorites and covered the spread, bringing their ATS record to 9-5. They are 6-2 as underdogs and 2-3 as favorites. Our power rankings have Arizona 14th, and they have a 12.6% chance of making the playoffs.
Heading into week 16, the Cardinals are 3rd in the NFC West with a 2-2 division record. They are 5-3 at home but just 2-4 on the road. Their O/U record is 6-7-1, with the over hitting in two straight games.
Arizona Cardinals Stats
We have the Cardinals ranked 12th in our offensive power rankings heading into week 16. They are 13th in the league in points per game (22.4) and 11th in total yards per game (351.4). Arizona has leaned on their run game, ranking 12th in rushing attempts and 6th in rushing yards per game (141.5). On 3rd down, they rank 9th in the NFL with a conversion rate of 42.9%.
Kyler Murray had a strong performance in week 15, going 23/30 for 224 yards without a turnover. James Conner rushed for 110 yards and 2 touchdowns on 16 carries, while Trey McBride led the team with 9 catches for 87 yards. Arizona scored 14 points in the 4th quarter and converted 10 of 15 3rd downs in their win over the Patriots.
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In their 30-17 win over the Patriots, the Arizona Cardinals’ defense allowed just 82.6% completions. They gave up 195 passing yards and one passing touchdown, with New England managing only 2 of 8 on third down. The Cardinals also came away with one interception and two sacks.
On the ground, the Cardinals gave up 116 rushing yards on 24 attempts, with New England averaging 4.8 yards per attempt. Arizona’s defense also had two sacks and four tackles for loss in the game.
Carolina Panthers
Heading into week 16, the Panthers sit at 3-11, putting them 32nd in our power rankings and giving them a 0.0% chance of making the playoffs. Carolina has now lost four straight games, including a 30-14 defeat to the Cowboys in week 15. The Panthers were 2.5-point favorites in that matchup, but they couldn’t get the win at home.
Against the spread, the Panthers are 6-8, with all six of their ATS wins coming as underdogs. Their average scoring margin this season is -12.2 points per game. Carolina’s O/U record is 10-4, with their games averaging 47.5 points per contest.
Carolina Panthers Stats
Carolina’s offense ranks 27th in our power rankings, averaging 17.6 points per game (25th in the NFL) and 288.9 yards per game, which is 30th in the league. They are 29th in passing yards, with 186 per game, on 32.7 attempts (15th). On the ground, they average 102.9 rushing yards per game (22nd) on 23.6 attempts (23rd). Carolina ranks 26th in 3rd-down conversions, with a rate of 34.7%, but they are 11th in the league in red zone conversion percentage.
Bryce Young threw for 219 yards (19/28) in week 15, with 1 touchdown and 2 interceptions, while being sacked 6 times. Chuba Hubbard had 32 rushing yards on 10 carries, and Jalen Coker led the team with 4 catches for 110 yards. Carolina scored 7 points in the 2nd and 4th quarters against Dallas, but were shut out in the 1st and 3rd quarters.
In their 30-14 loss to the Cowboys, the Panthers’ defense allowed 410 total yards and struggled to stop the run, giving up 211 rushing yards on 40 attempts. Despite limiting Dallas to 199 passing yards, Carolina allowed three passing touchdowns and a 62.1% completion rate. The Panthers also struggled on third down, allowing the Cowboys to convert 50% of their third down attempts.
Carolina’s defense managed just one sack in the game and lost the battle in both QB hits (-7) and tackles for loss (-6).
Arizona Cardinals vs. Carolina Panthers NFL Football Betting Trends
- The Cardinals are 2-3 in their last five games as a favorite.
- Conversely, the Panthers are 5-0 ATS in their last five games as an underdog.
- Also, the Cardinals are 7-3 ATS in their last ten road games.
- On the other side, the Panthers have gone 3-7 across their last ten home games.
- Over the Cardinals’ last 3 road games, the over/under record is 1-2.
- The Panthers’ have an over/under record of 1-2 in their last 3 games at home.
Cardinals vs. Panthers Line Movement
| Open-ML | Live-ML | Open-Spread | Live-Spread | |
|---|---|---|---|---|
| Cardinals | -118 | -207 | -1 | -4 |
| Panthers | -102 | +172 | +1 | +4 |
4* Free Week 16 NFL Betting Prediction: Carolina +4
The Panthers are 5-1 ATS in their last six games and have shown December resilience, covering six of their last nine in the final month.
Carolina has also owned the head-to-head matchup at home, going 5-1 straight up against Arizona in their last six Charlotte meetings. On the flip side, the Cardinals have struggled on the road, losing 14 of their last 18 outright.
With Carolina’s underdog energy meeting Arizona’s playoff push, this matchup promises action on both sides of the ball.
Our pick vs. the spread is to take the Panthers to cover as home underdogs. Right now, the point spread lines have the Panthers at +4, and we have the final score being 22-20 in favor of the Cardinals.
As for an over/under pick, with the line sitting at 47 points, we are leaning towards taking the under, with a projected combined score of 42 points.
Bank of America Stadium sets the stage for a fascinating battle with betting value that’s as exciting as the game itself!
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Arizona Cardinals vs. Carolina Panthers NFL Betting Tweet Of The Day
Dave Canales speaks to the media. https://t.co/eihQPnZSoW
— Carolina Panthers (@Panthers) December 18, 2024
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