Free AI NFL Prediction: Broncos at 49ers Odds
Looking for a free Denver Broncos at San Francisco 49ers AI computer prediction? Our NFL prediction model analyzes the matchup, betting odds, trends and available game data to produce today’s NFL computer pick. Scroll down for our Broncos at 49ers AI pick, projected score and best bet.
Denver Broncos at San Francisco 49ers AI Computer Picks & NFL Betting Analysis
- (2-1) Denver Broncos at San Francisco 49ers (3-0)
- Date: Sunday, October 4th
- Week: Week 4
- Time: 4:25 PM ET
- Venue: Levi’s Stadium Santa Clara, CA
- NFL Moneyline Odds: Broncos +121 | 49ers -145 (Bet Now!)
- NFL ATS Odds: Broncos +2.5 | 49ers -2.5
- NFL Betting Total: O/U: 47.5
CappersPicks uses artificial intelligence (AI) to analyze NFL data, betting odds and matchup trends for our daily computer picks. Our AI prediction model turns that data into free NFL computer predictions, projected scores and best bets. Scroll down for today’s Broncos at 49ers AI pick.
Offensive NFL Stats From Last Week
| Stat | Broncos | 49ers |
|---|---|---|
| PPG | 20 (17th) | 32.7 (2nd) |
| YPG | 275 (28th) | 399.3 (5th) |
| RUSH YPG | 81 (29th) | 136.3 (6th) |
| PASS YPG | 194 (20th) | 263 (5th) |
| 3 DOWN % | 36.1 (22nd) | 63 (1st) |
Defensive NFL Stats From Last Week
| Stat | Broncos | 49ers |
|---|---|---|
| PPG ALLWD | 23.3 (14th) | 16.7 (3rd) |
| YPG ALLWD | 380.7 (29th) | 313 (9th) |
| RUSH YPG ALLWD | 143.7 (28th) | 105.7 (14th) |
| PASS YPG ALLWD | 237 (24th) | 207.3 (14th) |
| TO | 4 (5th) | 2 (7th) |
| SACKS | 8 (6th) | 6 (8th) |
Broncos vs. 49ers Head-to-Head Trends for Our AI Prediction
- In the 2022 regular season, the Broncos edged out the 49ers with a score of 11-10 at Empower Field at Mile High.
- The last regular season game at Levi’s Stadium between these teams was in 2018, where the 49ers won 20-14.
- In their 2022 regular season meeting, the total points were under 45.0.
- The 2018 regular season game at Levi’s Stadium also ended with total points under 45.5.
Denver Broncos vs. San Francisco 49ers NFL Betting Trends
Before locking in your pick for the Denver Broncos vs. San Francisco 49ers matchup, take a look at some key betting trends. Indeed, both teams have shown strong patterns in specific spots — and these stats could help uncover where the value lies on today’s NFL betting card.
- The Broncos are 4-1 against the spread (ATS) in their last 5 regular season games as underdogs.
- San Francisco has won all 9 of their last regular season games as favorites.
- Denver is 5-1 straight up (SU) in their last 6 regular season away games.
- Also, the 49ers are 8-1 ATS in their last 9 regular season games as favorites.
- Additionally, the Broncos have gone over the total in 5 of their last 7 regular season games after a win.
- The 49ers have hit the over in all 5 of their last regular season games as favorites.
Broncos Injury Report
| Michael Deiter | Out (IR) | Quad |
| Jonathon Cooper | Out (Commissioner Exempt) | Commissioner Exempt List |
| Marvin Mims Jr. | Questionable | Foot |
| Matt Henningsen | Out (IR) | Achilles |
| Frank Crum | Out (IR) | Undisclosed |
| Nick Gargiulo | Out (PUP) | Knee |
| Levelle Bailey | Out (IR) | Leg |
| Jonah Coleman | Out (IR) | Ankle |
| Caleb Lohner | Out (IR) | Undisclosed |
49ers Injury Report
| Trent Williams | Questionable | Neck |
| Mike Evans | Questionable | Ribs |
| Demarcus Robinson | Out (IR) | Ankle |
| Christian Kirk | Out (IR) | Calf |
| Nick Bosa | Questionable | Calf |
| Dre Greenlaw | Questionable | Quadriceps |
| Brett Toth | Out (IR) | Concussion |
| Brandon Aiyuk | Out | Personal |
| Austen Pleasants | Out (IR) | Knee |
| Darrick Forrest | Out (IR) | Undisclosed |
| Nate Hobbs | Out (IR) | Groin |
| Nick Zakelj | Out (IR) | Elbow |
| Jake Tonges | Out (IR) | Knee |
| Sam Okuayinonu | Out (IR) | Foot |
| Andrew Farmer II | Out (IR) | Back |
| Ricky Pearsall | Out (IR) | Knee |
| Isaac Guerendo | Out (PUP) | Pectoral</ |
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Today’s Broncos at 49ers AI Computer Pick
NFL Free Score Prediction: Broncos 20 – 49ers 28 (Bet Now!) Our AI likes 49ers to win by 8.
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- 1% of your bankroll for 4* or less.
- 2% for 5* and 6*.
- Also, 4% for 7* or higher.
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Broncos at 49ers Odds for Our AI Computer Prediction
Below are the updated Broncos at 49ers NFL odds used by our AI prediction model.
Free NFL AI Computer Picks & Predictions
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