Free AI NFL Prediction: Bills at Patriots Odds
If you’re searching for Buffalo Bills at New England Patriots AI computer NFL football free predictions look no further! This game takes place on Sunday, December 14th at Gillette Stadium, in New England. At this time, our AI NFL computer prediction model has the gambling analysis, football betting trends, and outcome locked in. In fact, when you’re ready, just scroll down to get the free AI NFL pick.
NFL Handicapping – Buffalo Bills at New England Patriots AI NFL Football Prediction
- (9-4) Buffalo Bills at New England Patriots (11-2)
- Date: Sunday, December 14th
- Time: 1:00 PM ET
- Venue: Gillette Stadium New England, MA
- NFL Moneyline Odds: Bills -115 | Patriots -104 (Bet Now!)
- NFL ATS Odds: Bills -1.0 | Patriots +1.0
- NFL Betting Total: O/U: 49.5
As can be seen, artificial intelligence (AI) is used by CappersPicks.com to sort through vast quantities of data and identify the best outcomes for free computer picks on NFL football betting each day. For one thing, we save you tons of time and energy researching your selections by giving you our daily AI best bets. In fact, scroll down for today’s Buffalo Bills at New England Patriots AI NFL prediction.
Offensive NFL Stats
| Stat | Bills | Patriots |
|---|---|---|
| PPG | 525 (2nd) | 289 (28th) |
| YPG | 6105 (9th) | 4963 (32nd) |
| RUSH YPG | 2230 (9th) | 1969 (13th) |
| PASS YPG | 3875 (9th) | 2994 (32nd) |
| 3 DOWN % | 44.1 (7th) | 34.9 (25th) |
Defensive NFL Stats
| Stat | Bills | Patriots |
|---|---|---|
| PPG ALLWD | 368 (11th) | 417 (21st) |
| YPG ALLWD | 5806 (17th) | 5829 (22nd) |
| RUSH YPG ALLWD | 2230 (9th) | 1969 (13th) |
| PASS YPG ALLWD | 3875 (9th) | 2994 (32nd) |
| TO | 16 (4th) | 7 (12th) |
| SACKS | 39 (10th) | 28 (18th) |
Bills vs. Patriots AI Last Five Head To Head Trends
- In the 2025 season, the Patriots defeated the Bills 23–20 in Week 5, covering the spread of +7.5.
- The total went UNDER 49.5 in their 2025 Week 5 game.
- During the 2024 season, the Patriots won against the Bills 23–16 in Week 18, and the total went OVER 36.5.
- In the 2024 season, the Bills won 24–21 in Week 16, with the total going UNDER 48.0.
Buffalo Bills vs. New England Patriots NFL Betting Trends
Before locking in your pick for the Buffalo Bills vs. New England Patriots matchup, take a look at some key betting trends. Indeed, both teams have shown strong patterns in specific spots — and these stats could help uncover where the value lies on today’s NFL betting card.
- The Bills are 3-1 straight up as favorites in their last four games this season.
- Also, Buffalo has hit the over in 60% of their games with totals of 50 or more points in 2025.
- The Patriots are perfect at home, winning all five of their games at Gillette Stadium in 2025.
- New England is 4-1 against the spread as underdogs in their last five games.
- Additionally, the Patriots have covered the spread in 80% of their home games this season.
- Buffalo has struggled with the over in away games, going under in five of their last seven.
Bills Injury Report
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| Darius Slay | Out | Did Not Report |
| Joey Bosa | Questionable | Hamstring/Wrist |
| Curtis Samuel | Out | Elbow/Knee |
| Mecole Hardman | Out | Calf |
| Dawson Knox | Questionable | Personal |
| Ed Oliver | Out | Bicep |
| Taylor Rapp | Out | Knee |
| Damar Hamlin | Out | Pectoral |
| Tyler Bass | Out | Left Hip/Groin |
| Michael Hoecht | Out | Achilles |
| Joshua Palmer | Questionable | Knee/Ankle |
| Spencer Brown | Questionable | Shoulder |
| Terrel Bernard | Questionable | Elbow |
| Dalton Kincaid | Probable | Knee |
| Cole Bishop | Probable | Cramping |
| Landon Jackson | Out | Knee |
| DeWayne Carter | Out | Achilles |
| Dorian Strong |
Patriots Injury Report
| Harold Landry III | Questionable | Knee |
| Darius Harris | Out | Undisclosed |
| Craig Reynolds | Out | Undisclosed |
| Antonio Gibson | Out | Knee |
| Yasir Durant | Out | Undisclosed |
| Christian Barmore | Questionable | Non Injury Related |
| Milton Williams | Out | Ankle |
| Khyiris Tonga | Probable | Chest |
| Jashaun Corbin | Out | Undisclosed |
| Vederian Lowe | Questionable | Abdomen |
| Brenden Schooler | Probable | Ankle |
| Jaquelin Roy | Out | Undisclosed |
| Alex Austin | Out | Undisclosed |
| Deneric Prince | Out | Undisclosed |
| Terrell Jennings | Questionable | Concussion |
| Marcellas Dial Jr. | Out | ACL |
| Isaiah Iton | Out | Hip |
| Lan Larison</td |
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Today’s Free Bills at Patriots NFL Free AI Pick
NFL Free Score Prediction: Bills 27 – Patriots 24 (Bet Now!) Our AI likes Bills to win by 3.
NEXT NFL FOOTBALL AI PICK
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- 1% of your bankroll for 4* or less.
- 2% for 5* and 6*.
- Also, 4% for 7* or higher.
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Odds Comparison: Buffalo Bills at New England Patriots
Below are the updated Buffalo vs. New England NFL odds used by our AI prediction model.
20+ Years Handicapping NFL
Most important, with 20 years of handicapping data, our AI picks will deliver accurate predictions and easy-to-use tools to enhance your bets on every NFL football game we can get to. Hopefully you like our Buffalo Bills at New England Patriots AI NFL prediction today! After all, it’s a free NFL football pick, right? Enjoy!
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