Free AI NFL Prediction: Cardinals at Rams Odds
Looking for a free Arizona Cardinals at Los Angeles Rams AI computer prediction? Our NFL prediction model analyzes the matchup, betting odds, trends and available game data to produce today’s NFL computer pick. Scroll down for our Cardinals at Rams AI pick, projected score and best bet.
Arizona Cardinals at Los Angeles Rams AI Computer Picks & NFL Betting Analysis
- (1-4) Arizona Cardinals at Los Angeles Rams (2-3)
- Date: Sunday, October 18th
- Week: Week 6
- Time: 4:05 PM ET
- Venue: SoFi Stadium Inglewood, CA
- NFL Moneyline Odds: Cardinals +569 | Rams -826 (Bet Now!)
- NFL ATS Odds: Cardinals +13 | Rams -13
- NFL Betting Total: O/U: 52
CappersPicks uses artificial intelligence (AI) to analyze NFL data, betting odds and matchup trends for our daily computer picks. Our AI prediction model turns that data into free NFL computer predictions, projected scores and best bets. Scroll down for today’s Cardinals at Rams AI pick.
Offensive NFL Stats From Last Week
| Stat | Cardinals | Rams |
|---|---|---|
| PPG | 21.6 (18th) | 23.8 (12th) |
| YPG | 301.2 (23rd) | 424.4 (1st) |
| RUSH YPG | 91.6 (22nd) | 116.8 (12th) |
| PASS YPG | 209.6 (19th) | 307.6 (1st) |
| 3 DOWN % | 40.5 (12th) | 44.6 (6th) |
Defensive NFL Stats From Last Week
| Stat | Cardinals | Rams |
|---|---|---|
| PPG ALLWD | 32.4 (22nd) | 24 (12th) |
| YPG ALLWD | 363.4 (26th) | 285.2 (3rd) |
| RUSH YPG ALLWD | 126.6 (22nd) | 128.4 (24th) |
| PASS YPG ALLWD | 236.8 (25th) | 156.8 (2nd) |
| TO | 5 (5th) | 8 (8th) |
| SACKS | 11 (8th) | 8 (11th) |
Cardinals vs. Rams Head-to-Head Trends for Our AI Prediction
- In the 2025 regular season, the Rams defeated the Cardinals 37-20 at SoFi Stadium, covering the -14.0 spread and the total going over 48.5.
- During the 2025 regular season, the Rams won 45-17 against the Cardinals at State Farm Stadium, covering the -9.5 spread and the total going over 48.5.
- In the 2024 regular season, the Rams beat the Cardinals 13-9 at SoFi Stadium, covering the +6.5 spread with the total going under 48.0.
- On October 15, 2023, the Rams won 26-9 against the Cardinals at SoFi Stadium, covering the +7.0 spread with the total going under 47.5.
Arizona Cardinals vs. Los Angeles Rams NFL Betting Trends
Before locking in your pick for the Arizona Cardinals vs. Los Angeles Rams matchup, take a look at some key betting trends. Indeed, both teams have shown strong patterns in specific spots — and these stats could help uncover where the value lies on today’s NFL betting card.
- The Cardinals are 3-0 on the over/under in their last three regular season games after a loss.
- Arizona has hit the over in three out of their last four away games in the regular season.
- Also, the Rams are 3-0 on the over/under as favorites in their last three regular season games.
- Los Angeles has a strong 9-2 record on the over/under in their last 11 regular season games.
- Additionally, the Rams have won six of their last eight regular season home games straight up.
- Los Angeles is 4-2 against the spread in their last six regular season home games.
Cardinals Injury Report
| James Conner | Out (IR) | Foot |
| Andrew Wingard | Questionable | Knee |
| Hunter Long | Out (IR) | Knee |
| Zach Carter | Out (IR) | Knee |
| Joey Blount | Out (IR) | Neck |
| Paris Johnson Jr. | Out (IR) | Biceps |
| Trey Benson | Out (IR) | Knee |
| Isaiah Adams | Out (IR) | Ankle |
| Tip Reiman | Out (PUP) | Ankle |
| Will Johnson | Out (IR) | Neck |
| Kitan Crawford | Out (IR) | Ankle |
| Chase Bisontis | Out (IR) | Knee |
| Kaleb Proctor | Out (IR) | Knee |
| Jameson Geers | Out (IR) | Undisclosed |
Rams Injury Report
| Myles Garrett | Out (IR) | Knee |
| Ronnie Rivers | Out (IR) | Calf |
| Alaric Jackson | Out | Suspended |
| Keir Thomas | Out (IR) | Undisclosed |
| Justin Dedich | Out (IR) | Undisclosed |
| Terrance Ferguson | Out (IR) | Ankle |
| Keagen Trost | Out (IR) | Undisclosed |
| Matthew Caldwell | Out (IR) | Undisclosed |
| Eddie Walls III | Out (IR) | Leg |
| Daniel Rickert | Out (IR) | Knee |
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Today’s Cardinals at Rams AI Computer Pick
NFL Free Score Prediction: Cardinals 17 – Rams 31 (Bet Now!) Our AI likes Rams to win by 14.
NEXT NFL FOOTBALL AI PICK
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- 1% of your bankroll for 4* or less.
- 2% for 5* and 6*.
- Also, 4% for 7* or higher.
Expert NFL Betting Picks
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Cardinals at Rams Odds for Our AI Computer Prediction
Below are the updated Cardinals at Rams NFL odds used by our AI prediction model.
Free NFL AI Computer Picks & Predictions
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