Free NCAAF Pick: Nittany Lions vs. Buckeyes Odds
Looking for Penn State Nittany Lions vs. Ohio State Buckeyes Free NCAA Week 10 picks & NCAA odds? NCAAF betting sees the Nittany Lions taking on the Buckeyes on 11/1 at Ohio Stadium, in Ohio State. Cappers Picks provides complimentary expert handicapping picks on all NCAA football matchups all season long so stay tuned for more FREE daily NCAAF predictions like this Nittany Lions Buckeyes free pick.
2025 NCAAF Handicapping – Penn State Nittany Lions vs Ohio State Buckeyes
(3-4) Penn State Nittany Lions vs. Ohio State Buckeyes (7-0)
Date: Nov 01, 2025
Time: 12:00 PM ET
Venue: Ohio Stadium in Ohio State, OH
NCAAF Moneyline Odds: Nittany Lions +847 | Buckeyes -1623 (Bet Now!)
Today’s NCAAF Spread Betting Odds: Nittany Lions +20.5 | Buckeyes -20.5
NCAAF Football Gambling Total: O/U: 43.5
Here’s why I’m backing an Ohio State ATS bet below in my Nittany Lions Buckeyes free pick & gambling prediction for this matchup.
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Nittany Lions vs. Buckeyes Gameday
It’s Week 10, and the focus is on Penn State vs. Ohio State — a classic Big Ten collision inside The Horseshoe. The game kicks off Saturday at 12:00 PM ET on FOX, with Columbus ready to roar.
Penn State enters as a bruised but dangerous 3-4 squad, still searching for their first conference win. They’re 0-2 on the road and clearly need a spark before this season slips away.
What’s more, Ohio State is every bit the juggernaut.
Sitting undefeated at 7-0, ranked No. 1 across the board, and 4-0 at home — the Buckeyes have made dominance look boring.
Historically, this matchup hasn’t been kind to Penn State. Ohio State has taken the last five meetings, including last season’s 20-13 grinder. The Nittany Lions need something close to a miracle if they want to rewrite the script in Columbus.
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It’s Week 10: Penn State Nittany Lions vs. Ohio State Buckeyes. Buckle up — this could get lopsided fast.
Penn State Nittany Lions vs. Ohio State Buckeyes Odds & Last 5
Oddsmakers aren’t exactly giving Penn State much hope. They’re massive +927 underdogs on the moneyline, while Ohio State sits at -1669, which is Vegas shorthand for “good luck.”
Meanwhile, the spread is set at 20.5, with both sides priced evenly at -110. In other words, the market expects another Buckeye beatdown unless Penn State’s defense suddenly wakes up. The Over/Under is holding steady around 54, signaling potential for points — mostly from one team.
Ohio State’s dominance in this series is well-documented. Their last meeting ended 20-13, and that was considered a “close” one.
The Lions need more than grit; they need touchdowns — fast.
Buckeyes Stats
Offensively, Ohio State hasn’t been quite as explosive as past seasons, but they’re still top-tier. They rank 32nd nationally in total points (255), 46th in passing yards (1,958), and 84th in rushing yards (1,082). There’s room to improve on the ground, yet it hasn’t mattered much.
Defensively, the Buckeyes are pure misery for opponents. They’ve allowed only 41 points (9th nationally) while racking up 21 sacks (10th). Add in 4 interceptions and 4 fumble recoveries — both top-10 marks — and you see why they’re cruising.
Their recent run has been ruthless: Wisconsin 34-0, Illinois 34-16, Minnesota 42-3. This team doesn’t play with its food; it devours it.
Quarterback Julian Sayin is the conductor, piling up 1,872 passing yards and 19 touchdowns.
Freshman phenom Jeremiah Smith has 602 receiving yards and seven TDs, while Jayden Fielding remains automatic in the kicking game.
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Nittany Lions Stats
Penn State’s offense, on the other hand, looks like it’s stuck in neutral. They rank 111th in passing (1,298 yards) and 69th in rushing (1,187). The ground game keeps them somewhat afloat, but consistency has been a major issue.
Their defense has bright spots — ranking 6th in interceptions (5) and 7th in fumbles recovered (4). Still, allowing 136 total points (62nd) tells the real story. They just can’t keep pace against elite competition.
The Nittany Lions’ last two games were heartbreakers — losses to Iowa (25-24) and Northwestern (22-21) — the kind of defeats that drain locker rooms. Worse, injuries have piled up.
Losing quarterback Drew Allar for the season hurt, and several key players remain questionable heading into Columbus.
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Nittany Lions vs. Buckeyes QB Matchup
Julian Sayin has been a revelation for Ohio State. The freshman has 1,872 yards and 19 touchdowns with just three picks — calm, efficient, and downright clinical.
Backup Lincoln Kienholz has seen light work, throwing for 86 yards and a score, but this is Sayin’s show now.
For Penn State, Drew Allar’s season-ending injury forces Ethan Grunkemeyer into the spotlight.
Allar posted 1,100 yards and eight touchdowns before going down, while Grunkemeyer’s relief work (198 yards, one TD, two INTs) has been shaky at best.
This quarterback matchup feels like a mismatch — a Ferrari vs. a flat tire.
Bottom Line: Penn State Nittany Lions vs. Ohio State Buckeyes: Ohio State is built to crush teams like this. Penn State’s defense might hang around early, but eventually, the Buckeyes’ depth and passing attack should overwhelm them.
Penn State Nittany Lions vs. Ohio State Buckeyes Football Betting Trends
- Penn State is 5-0 on the Over/Under in their last 5 away games.
- Ohio State is 28-2 straight up in their last 30 home games.
- Penn State is 9-3 straight up after a loss in their last 12.
- Also, Ohio State is 27-2 straight up as a favorite in their last 29.
- Additionally, Penn State is 17-8 against the spread in their last 25 away games.
- Ohio State is 4-0 against the spread in their last 4 games after a win.
Nittany Lions Buckeyes Free Pick: Ohio State -20.5
Here is my Nittany Lions Buckeyes free pick. Without a doubt, the Ohio State Buckeyes are a powerhouse at home, winning an incredible 28 of their last 30 games in Columbus. Their consistency inside the Horseshoe makes them one of the toughest teams in college football to knock off.
Moreover, the Buckeyes’ defense has been lights-out, ranking inside the top ten nationally in points allowed.
This group simply smothers opposing offenses and forces them into uncomfortable situations early and often.
Meanwhile, Penn State hasn’t traveled well, going 0-2 on the road this year and still searching for their first conference victory. Even with a solid roster, their lack of rhythm outside Happy Valley is alarming, especially against such a disciplined opponent.
Additionally, while Ohio State’s offense may not post video-game numbers like last season, their aerial attack remains dangerous. They can easily exploit Penn State’s shaky secondary and build an early lead that forces the Nittany Lions to play catch-up all afternoon.
Given their home dominance, defensive strength, and proven ability to cover big numbers, laying the -20.5 with Ohio State feels like the right call.
The Buckeyes should roll comfortably in this one and remind everyone why they’re still the team to beat in the Big Ten.
Today’s NCAAF Free Pick
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NCAAF Betting Tweet Of The Day
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