Free NCAAF Pick: Tigers vs. Rebels Odds
Looking for LSU Tigers vs. Ole Miss Rebels Free NCAA Week 5 picks & NCAA odds? NCAAF betting sees the Tigers taking on the Rebels on 9/27 at Vaught-Hemingway Stadium, in Ole Miss. Cappers Picks provides complimentary expert handicapping picks on all NCAA football matchups all season long so stay tuned for more FREE daily NCAAF predictions like this Tigers Rebels free pick.
2025 NCAAF Handicapping – LSU Tigers vs Ole Miss Rebels
(4-0) LSU Tigers vs. Ole Miss Rebels (4-0)
Date: Sep 27, 2025
Time: 3:30 PM ET
Venue: Vaught-Hemingway Stadium in Ole Miss, MS
NCAAF Moneyline Odds: Tigers +100 | Rebels -121 (Bet Now!)
Today’s NCAAF Spread Betting Odds: Tigers +1.5 | Rebels -1.5
NCAAF Football Gambling Total: O/U: 54.5
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Tigers vs. Rebels Gameday
The LSU Tigers are ready to travel to Vaught-Hemingway Stadium. They come in with a 4-0 record and a #4 ranking in both the AP and Coaches Poll. Their recent win was a dominant 56-10 victory over Southeastern Louisiana.
On the other side, Ole Miss Rebels are also undefeated at 4-0. They are ranked #13 in the AP Poll and #11 in the Coaches Poll. Their latest triumph was a 45-10 win against Tulane at home.
Additionally, both teams have a history of competitive games. The last time they met in 2023, Ole Miss won 55-49 at home. This game looks to add another chapter to their rivalry.
Finally, this game will be broadcast on ABC at 3:30 PM ET. With both teams on a winning streak, fans can expect an exciting afternoon. The outdoor setting at Vaught-Hemingway Stadium will provide the perfect backdrop for this SEC showdown.
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It’s Week 5, LSU Tigers vs. Ole Miss Rebels, hopefully we get a great matchup.
LSU Tigers vs. Ole Miss Rebels Odds & Last 5
The odds for this game show a tight contest between LSU and Ole Miss. The consensus moneyline has LSU at -101 and Ole Miss at -119. The spread is a close +1.5 for LSU and -1.5 for Ole Miss, with the total set at 54.5.
Looking back, LSU has shown strong performances this season. They kicked off the season with a 17-10 win against Clemson, then followed with wins against Louisiana Tech and Florida. They capped it off with a 56-10 victory over Southeastern Louisiana.
Meanwhile, Ole Miss has had a notable run too. They started with a commanding 63-7 win over Georgia State. They continued their success with victories against Kentucky, Arkansas, and a solid 45-10 win against Tulane.
Rebels Stats
To start, Ole Miss Rebels have been strong on offense this season. They have scored 179 points, ranking 10th in the league. Their passing game is also impressive with 1,299 yards, placing them 9th overall.
Next, the Rebels’ defense has held opponents to 75 points, which ranks 50th. They have managed to secure 4 sacks and 2 interceptions, showing their defensive strength. Additionally, they have recovered 1 fumble, ranking 5th in this category.
Recently, Ole Miss has been on a winning streak. They won their last four games, with the most recent victory against Tulane Green Wave, ending 45-10. In that game, they achieved 307 passing yards and 241 rushing yards, showing their offensive balance.
Finally, key players have been stepping up for the Rebels. Trinidad Chambliss leads the team in passing yards with 719 and has thrown 4 touchdowns.
On the ground, Kewan Lacy has rushed for 358 yards and scored 7 touchdowns, making him a vital part of their offense.
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Tigers Stats
To begin, the LSU Tigers have been on a roll this season. They have won all four games, including a significant 56-10 win against Southeastern Louisiana. Their offense is ranked 23rd in passing yards with 1,098 yards this season.
Additionally, Garrett Nussmeier leads the team as the quarterback. He has thrown for 960 yards and six touchdowns over four games. However, Nussmeier has also thrown two interceptions during this stretch.
On the ground, Caden Durham has been the primary running back. He has rushed for 213 yards and scored two touchdowns. Durham is currently dealing with an ankle sprain, which may impact his availability.
Defensively, LSU has been strong, allowing only 37 points across four games. They rank 15th in points against and 7th in both sacks and interceptions. The defense’s ability to pressure opposing quarterbacks has been key to their success.
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Tigers vs. Rebels QB Matchup
Trinidad Chambliss leads the Ole Miss Rebels with 719 passing yards over four games. He sits first on the team in both passing yards and touchdowns, having thrown four scores without a single interception.
Austin Simmons, the second quarterback for Ole Miss, has appeared in three games and thrown for 580 yards. He’s also tossed four touchdowns, though his four interceptions highlight a riskier style of play.
For LSU, Garrett Nussmeier has been the clear leader under center. Through four games, he’s piled up 960 passing yards with six touchdowns against two interceptions, pacing the Tigers in every major passing category.
Michael Van Buren Jr. has seen limited action, playing in one game but still contributing 122 passing yards and a touchdown without a turnover.
That puts him second on the team in passing yards despite the small sample size.
LSU Tigers vs. Ole Miss Rebels Football Betting Trends
- LSU is 6-0 straight up in their last 6 games overall.
- Additionally, LSU has gone 15-10 on the over/under in their last 25 games after a win.
- LSU is 11-9 against the spread as an underdog in their last 20 games.
- Ole Miss is 27-3 straight up in their last 30 home games.
- Also, Ole Miss has a 21-3 straight-up record as a favorite in their last 24 games.
- Ole Miss is 9-4 against the spread after a win in their last 13 games.
Tigers vs Rebels Prediction: Over 54.5
LSU and Ole Miss both bring explosive offenses to the table, with the Rebels ranking 10th nationally in points scored and the Tigers not far behind in overall production.
This offensive firepower sets the stage for another track meet when these two square off.
History also leans heavily toward points, as last year’s clash turned into a wild 104-point shootout. With both teams showing little resistance in prior matchups, it’s hard to imagine a low-scoring affair this time around.
LSU trends toward the over after wins (15-10), while Ole Miss thrives at home, giving every indication this one has fireworks written all over it.
Additionally, both squads feature quarterbacks who can stretch the field and running games capable of breaking chunk plays. That balance ensures neither side is one-dimensional, making it tougher for defenses to key in and slow the tempo.
Considering the recent head-to-head history and the fact that both programs are built on offensive pace, betting the over 54.5 looks like the sharp side.
Expect another high-octane SEC showdown with plenty of touchdowns on the board.
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NCAAF Betting Tweet Of The Day
Game 0️⃣5️⃣
🆚 LSU
📍 Oxford, MS
🏟️ Vaught-Hemingway Stadium
🕝 2:30 PM CT
📺 ABC#HottyToddy pic.twitter.com/ipLLN1Yz5C— Ole Miss Football (@OleMissFB) September 23, 2025
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