Free NCAA Pick: Kentucky vs. South Carolina Odds
Looking for Kentucky Wildcats vs. South Carolina Gamecocks free NCAA Week 5 picks & NCAA odds? NCAA betting sees the Wildcats taking on the Gamecocks on Saturday, September 27 at Williams-Brice Stadium (SC). Cappers Picks provides complimentary NCAA handicapping picks all season long including all NCAA Week 5 games so stay tuned for more FREE NCAA predictions like this Kentucky South Carolina matchup.
2025 NCAAF Handicapping Analysis: Kentucky Wildcats vs. South Carolina Gamecocks Week 5
(2-1) Kentucky Wildcats vs. South Carolina Gamecocks (2-2)
Date: Saturday, September 27, 2025
Time: 7:30PM
Venue: Williams-Brice Stadium, Greenville, South Carolina
Week 5 ATS Betting Lines: (BET NOW!) Kentucky +6 | South Carolina -6
Week 5 CFB Moneyline Odds: Kentucky +180 | South Carolina -218
College Football Betting Total: O/U 47.5
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Both of these teams are looking for their first SEC win. If they don’t get it, especially South Carolina, you have to wonder if they will.
The Gamecocks have especially been a disappointment after a strong finish to last season and Lanoris Sellers a highly thought of quarterback.
At Kentucky, Mark Stoops might be running out of road. He has been overall more successful than expected, but things are fading.
Kentucky is the underdog and that is always how you want to back the Wildcats, who are often about effort and overcoming.
Kentucky Wildcats
Even though QB Zach Calzada has a ton of experience it looks like the Wildcats are turning the job over to Cutter Boley. The better long term solution.
This will be a serious test, facing an SEC opponent that can get after the passer, and on the road. He is mobile enough so he will not be a sitting duck back there though.
Both the offense and defense have struggled when taking on Power 5 opponents, so this game is an indicator of where the program is at compared to its peers.
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Kentucky Wildcats Stats
In 2025, the rushing attack has been a key strength, averaging an impressive 214.7 yards per game.
Running back Seth McGowan leads the team’s potent rushing attack, accumulating 275 yards and a team-high 6 touchdowns on 51 carries, while averaging 5.4 yards per attempt.
Fellow running back Dante Dowdell has also been highly effective, averaging 5.9 yards per carry with 214 yards and 1 touchdown on 36 attempts.
The passing game has been less efficient, with the team averaging just 170.7 passing yards per game with a collective completion percentage of .
The defense has given up an average of 278.3 passing yards and 136.7 rushing yards per game, yielding a total of 415.0 yards per contest to opposing offenses.
Despite the struggles in team passing efficiency, tight end Josh Kattus has been a reliable target with 8 receptions for 112 yards and 1 touchdown, while wide receiver Jay Maclin has led the team in receiving yards with 103 on just 4 catches, showcasing a high yards-per-reception average.
Overall, the Wildcats are averaging 31.7 points per game while allowing 23.0, indicating a tendency toward high-scoring affairs, particularly when their powerful rushing game is on track.
South Carolina Gamecocks
Sellers was a legit Heisman hopeful before the season. If you are betting on him now, you are really taking a risk, though.
The talent is there but he has just not taken the leap. Last year he was solid in an easy win for SC against Kentucky so maybe that will help.
The Gamecocks’ defense was supposed to be fearsome this season but we have not seen that against SEC foes. Kentucky is not as good on offense as Vandy or Mizzou though.
This is a get right spot for the home team, and they need it after and 0-2 start in the SEC.
South Carolina Gamecocks Stats
Offensively, the team is averaging just points per game.
Quarterback LaNorris Sellers has been the primary passer, throwing for yards and four touchdowns. However, the team’s rushing attack has struggled, averaging only yards per attempt, with Rahsul Faison currently leading the rushers with yards and one touchdown.
The offense’s struggles are highlighted by a low third-down conversion rate of just .
On the defensive side, South Carolina has been slightly more effective, holding opponents to points and total yards per game.
The run defense allows rushing yards per game at yards per carry, while the pass defense has been stronger, limiting opponents to yards through the air.
The Gamecocks have shown an ability to create turnovers, with the defense totaling four interceptions through the first four games..
- The total has gone OVER in 5 of Kentucky’s last 7 games.
- Kentucky is 3-7 SU in its last 10 games.
- Kentucky is 8-4 ATS in its last 12 games against South Carolina.
- Kentucky is 2-4 SU in its last 6 games against South Carolina.
- South Carolina is 11-5 ATS in its last 16 games.
- The total has gone UNDER in 5 of South Carolina’s last 6 games.
- South Carolina is 8-3 SU in its last 11 games.
- The total has gone UNDER in 9 of South Carolina’s last 10 games against Kentucky.
4* Free Kentucky Wildcats vs. South Carolina Gamecocks 2025 Week 5 NCAA Betting Prediction: South Carolina -6
I never bought into South Carolina as a playoff contender, though I could see how others did given the way they finished last season.
The offense just isn’t there and I would expect lots of bettors are putting this game into their teasers given that we are on the key number right now.
Their early results drop this number to one where it very comfortable and even better if you want to include in a teasers.
The Gamecocks can play from ahead throughout, and Kentucky is not built to play catch-up, especially against a team that can rush the passer.
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Kentucky vs. South Carolina NCAA Betting Tweet Of The Day
See you there 🤙 pic.twitter.com/FRDs9bzzIs
— South Carolina Football (@GamecockFB) September 26, 2025
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