
Free NCAAF Pick: Hoosiers vs. Boilermakers Odds
Looking for Indiana Hoosiers vs. Purdue Boilermakers Free NCAA Week 14 picks & NCAA odds? NCAAF betting sees the Hoosiers taking on the Boilermakers on 11/28 at Ross-Ade Stadium, in West Lafayette, IN. Cappers Picks provides complimentary expert handicapping picks on all NCAA football matchups all season long so stay tuned for more FREE daily NCAAF predictions like this Hoosiers Boilermakers free pick.
2025 NCAAF Handicapping – Indiana Hoosiers vs Purdue Boilermakers
(11-0) Indiana Hoosiers vs. Purdue Boilermakers (2-9)
Date: Nov 28, 2025
Time: 7:30 PM ET
Venue: Ross-Ade Stadium in West Lafayette, IN
NCAAF Moneyline Odds: Hoosiers -9000 | Boilermakers +1937 (Bet Now!)
Today’s NCAAF Spread Betting Odds: Hoosiers -28.5 | Boilermakers +28.5
NCAAF Football Gambling Total: O/U: 54.5
Here’s why I’m backing an Indiana ATS bet below in my Hoosiers Boilermakers free pick & gambling prediction for this matchup.
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Hoosiers vs. Boilermakers Gameday
Indiana Hoosiers and Purdue Boilermakers meet under the Friday night lights at Ross-Ade Stadium for their Week 14 rivalry showdown. The stage is set in West Lafayette with NBC carrying the broadcast to a national audience.
Purdue has faced tough losses, including a recent defeat against Washington.
Indiana enters undefeated at 11-0 and sits at #2 in both major polls, a testament to their balance on offense and reliability on defense. Even so, rivalry games tend to break patterns, and the Hoosiers know they’ll need to maintain sharp execution to keep their perfect record intact.
Purdue sits at 2-9 and remains winless in conference play, but their earlier effort against Michigan showed flashes of competitive resolve. Likewise, the Boilermakers will try to lean into that fight as they look to disrupt Indiana’s postseason aspirations.
Last year’s 66-0 Indiana win still lingers, though Purdue claimed the 2023 meeting.
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It’s Week 14, Indiana Hoosiers vs. Purdue Boilermakers, and both sides enter with their own motivations.
Indiana Hoosiers vs. Purdue Boilermakers Odds & Last 5
Indiana enters as a massive favorite with a -7900 moneyline and a 28.5-point spread advantage. Purdue sits at +1900, reflecting the wide gap between the programs this season.
Indiana has delivered quality wins over Wisconsin, Penn State, and Maryland, showing consistent dominance on both sides of the ball. Instead, their recent margins reflect a team that knows how to finish drives and control momentum.
Purdue’s recent stretch has been challenging with losses to Washington and Ohio State, though their close call against Michigan showed they can stay competitive when the matchup suits them.
Indiana has covered in multiple recent games.
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Boilermakers Stats
Purdue’s offense has posted 222 points this season, placing them 95th nationally. Their passing game has produced 2,368 yards, while the rushing attack sits at 1,478 yards with room for more explosive plays.
Their defense has allowed 326 points to rank 127th, yet their disruptive ability stands out with four interceptions, four fumble recoveries, and 24 sacks. In turn, this unit performs better in pressure moments than the scoring totals might suggest.
Purdue’s recent losses to Washington and Ohio State highlighted offensive inconsistency, producing only modest yardage through the air and on the ground. At the same time, key injuries — especially the loss of Devin Mockobee — have limited options.
Quarterback Ryan Browne has thrown for 1,915 yards with nine touchdowns, keeping the passing game functional despite roster challenges.
Hoosiers Stats
Indiana’s offense has been one of the most efficient in the country, ranking second in scoring with 476 points. Their 2,475 rushing yards place them in the national top ten with a physical, punishing ground attack.
The defense has also carried its weight, recording 33 sacks and 16 interceptions to anchor a top-20 national unit. Overall, the Hoosiers combine pressure, ball skills, and disciplined tackling to create difficult matchups for opposing quarterbacks.
Indiana’s last five wins include dominant efforts over Wisconsin, Penn State, and Maryland, featuring balanced scoring and sharp execution. Several injuries have surfaced in recent weeks, though the depth chart has held firm.
Quarterback Fernando Mendoza leads with 2,641 passing yards and 30 touchdowns, providing steady command throughout the season.
Hoosiers vs. Boilermakers QB Matchup
Purdue’s Ryan Browne has thrown for 1,915 yards with nine touchdowns and nine interceptions, reflecting both upside and volatility in his play. Backup Malachi Singleton adds 439 yards with five touchdowns and two interceptions in supporting duty.
Indiana counters with Fernando Mendoza, who’s delivered 2,641 passing yards, 30 touchdowns, and just five interceptions. His accuracy and decision-making remain key components of Indiana’s undefeated campaign.
Alberto Mendoza provides depth with 210 passing yards and four touchdowns across six appearances.
Indiana Hoosiers vs. Purdue Boilermakers bottom line: Indiana’s balance on offense and relentless pressure on defense position them to control this matchup, but Purdue’s rivalry edge could help them keep stretches competitive if they avoid early mistakes.
Indiana Hoosiers vs. Purdue Boilermakers Football Betting Trends
- Indiana is 21-0 straight up in their last 21 games as favorites.
- Indiana is 4-0 straight up in their last 4 away games.
- Indiana is 14-6 against the spread in their last 20 games as favorites.
- Also, the total has gone over in 13 of Indiana’s last 18 games with totals of 50 or more.
- Additionally, Purdue is 2-1 against the spread in their last 3 games as underdogs.
- The total has gone over in 17 of Purdue’s last 29 games after a loss.
Hoosiers Boilermakers Free Pick: Indiana -28.5
Here is my Hoosiers Boilermakers free pick. Indiana has been automatic in the favorite role, winning 21 straight when laying points and covering in 14 of their last 20 as chalk.
They’ve also been flawless on the road this season at 4-0, showing their offense and tempo travel with ease.
Purdue, meanwhile, is limping to the finish line with a 2-9 record and a brutal nine-game losing streak. Their defense has been a major liability, giving up 326 points — 127th nationally — and that’s a dangerous matchup against an Indiana offense that ranks second in the country in scoring.
My system tells me Indiana’s offensive firepower and Purdue’s defensive collapse make -28.5 the right side.
With Indiana rolling and Purdue struggling in every key metric, the Hoosiers have a clear path to stretching this margin early and never letting up. Indiana -28.5 is the pick.
Today’s NCAAF Free Pick
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NCAAF Betting Tweet Of The Day
Edition No. 100 on Friday night ⏳ pic.twitter.com/auUxkr1Emk
— Purdue Football (@BoilerFootball) November 25, 2025
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