Free AI NCAA Football Prediction: Duke at Virginia Odds
Looking for a free Duke Blue Devils at Virginia Cavaliers AI computer prediction? Our NCAA football prediction model analyzes the matchup, betting odds, trends and available game data to produce today’s NCAA football computer pick. Scroll down for our Duke at Virginia AI pick, projected score and best bet.
Duke Blue Devils at Virginia Cavaliers AI Computer Picks & NCAA Football Betting Analysis
- (4-2) Duke Blue Devils at Virginia Cavaliers (4-3)
- Date: Friday, October 23rd
- Time: 7:00 PM ET
- Venue: Scott Stadium in Charlottesville, VA
- NCAAF Moneyline Odds: Duke +101 | Virginia -123 (Bet Now!)
- NCAAF ATS Odds: Duke +1.5 | Virginia -1.5
- NCAAF Betting Total: O/U: 47.5
CappersPicks uses artificial intelligence (AI) to analyze NCAA football data, betting odds and matchup trends for our daily computer picks. Our AI prediction model turns that data into free NCAA football computer predictions, projected scores and best bets. Scroll down for today’s Duke at Virginia AI pick.
Offensive NCAA Football Stats
| Stat | Duke | Virginia |
|---|---|---|
| PPG | 27.1 (49th) | 30.0 (37th) |
| YPG | 380.6 (54th) | 363.7 (63rd) |
| RUSH YPG | 180.7 (35th) | 157.9 (56th) |
| PASS YPG | 199.9 (74th) | 205.7 (70th) |
Defensive NCAA Football Stats
| Stat | Duke | Virginia |
|---|---|---|
| PPG ALLWD | 96 (50th) | 138 (78th) |
| TO | 1 (2nd) | 7 (8th) |
| SACKS | 13 (13th) | 14 (12th) |
Duke vs. Virginia Head-to-Head Trends for Our AI Prediction
- Duke won the last game against Virginia in December 2025, with a score of 27–20.
- The total went under in both 2025 meetings between Duke and Virginia.
- Virginia covered the spread in their November 2025 game against Duke.
- Duke covered the spread in their December 2025 game against Virginia.
Duke Blue Devils vs. Virginia Cavaliers NCAA Football Betting Trends
Before locking in your pick for the Duke Blue Devils vs. Virginia Cavaliers matchup, take a look at some key betting trends. Indeed, both teams have shown strong patterns in specific spots — and these stats could help uncover where the value lies on today’s NCAA football betting card.
- The Blue Devils are 3-0 straight up in their last three games as underdogs.
- Duke is 3-0 against the spread in their last three games as underdogs.
- Virginia is 6-0 straight up after a loss in their last six games.
- The Cavaliers are 4-0 straight up in their last four home games.
- Also, the Blue Devils have hit the over in 17 of their last 23 away games.
- Additionally, the Cavaliers are 14-5 against the spread after a loss in their last 19 games.
Duke Injury Report
| Player | Status | Injury |
|---|---|---|
| Matt Craycraft (OL) | Questionable | |
| Evan Smith (CB) | Questionable | |
| Reagan McCranie (OL) | Questionable | |
| Cosme Salas (K) | Out | |
| Jamien Little (WR) | Questionable | |
| Elliott Schaper (LB) | Questionable | |
| Qeanu Johnson (RB) | Questionable | |
| Kai Jacobowitz (OL) | Questionable | |
| Roman Fina (OL) | Questionable | |
| Lawrence Gardner (QB) | Questionable | |
| Blake Rohrer (WR) | Questionable |
Virginia Injury Report
| Player | Status | Injury |
|---|---|---|
| Noah Hartsoe (OL) | Questionable | |
| Brandyn Hillman (S) | Questionable | |
| Rico Flores Jr. (WR) | Out | Knee |
| Jason Hammond (DT) | Questionable | |
| Caleb Hardy (LB) | Questionable | |
| Omillio Agard (CB) | Questionable | |
| Chase Morrison (DT) | Questionable | |
| Kameron Courtney (WR) | Questionable | |
| Tyler Simmons (DT) | Out | |
| Triston Ward (WR) | Out | |
| Jewett Hayes (DE) | Questionable | |
| Grant Ellinger (OL) | Questionable | |
| Peyton Lewis (RB) | Questionable | </ |
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Today’s Duke at Virginia AI Computer Pick
NCAA Football Free Score Prediction: Blue Devils 24 – Cavaliers 21 (Bet Now!) Our AI likes Blue Devils to win by 3.
NEXT NCAA FOOTBALL AI PICK
Interestingly, Duke has been strong as an underdog, winning their last three games in this role. Their defense ranks high in interceptions and fumbles recovered, which could make the difference in a close game.
Not sure what amount to bet on this Duke at Virginia AI NCAA Football prediction? Just like our experts we give star ratings on our plays. So far, these AI NCAA football computer picks are rated 4*.
- 1% of your bankroll for 4* or less.
- 2% for 5* and 6*.
- Also, 4% for 7* or higher.
Expert NCAA Football Betting Picks
Need a few more angles for this week’s college football slate? Browse today’s featured premium plays from CappersPicks handicappers, with sides, totals, moneylines, and other NCAA football bets.
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Duke Blue Devils vs. Virginia Cavaliers Betting
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Duke at Virginia Odds for Our AI Computer Prediction
Below are the updated Duke at Virginia NCAA football odds used by our AI prediction model.
Free NCAA Football AI Computer Picks & Predictions
With 20+ years of CappersPicks handicapping data, our AI prediction model analyzes NCAA football matchups, betting trends and odds to produce free NCAA football computer picks and score predictions. Check back daily for our latest AI NCAA football picks, including today’s Duke Blue Devils at Virginia Cavaliers AI prediction.
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