Free AI NCAA Football Prediction: Ohio State at Indiana Odds
Looking for a free Ohio State Buckeyes at Indiana Hoosiers AI computer prediction? Our NCAA football prediction model analyzes the matchup, betting odds, trends and available game data to produce today’s NCAA football computer pick. Scroll down for our Ohio State at Indiana AI pick, projected score and best bet.
Ohio State Buckeyes at Indiana Hoosiers AI Computer Picks & NCAA Football Betting Analysis
- (5-1) Ohio State Buckeyes at Indiana Hoosiers (6-0)
- Date: Saturday, October 17th
- Time: 12:00 PM ET
- Venue: Memorial Stadium (Bloomington, IN) in Bloomington, IN
- NCAAF Moneyline Odds: Ohio State -174 | Indiana +143 (Bet Now!)
- NCAAF ATS Odds: Ohio State -3.5 | Indiana +3.5
- NCAAF Betting Total: O/U: 51
CappersPicks uses artificial intelligence (AI) to analyze NCAA football data, betting odds and matchup trends for our daily computer picks. Our AI prediction model turns that data into free NCAA football computer predictions, projected scores and best bets. Scroll down for today’s Ohio State at Indiana AI pick.
Offensive NCAA Football Stats
| Stat | Ohio State | Indiana |
|---|---|---|
| PPG | 256 (4th) | 241 (11th) |
| YPG | 2027 (4th) | 1448 (42nd) |
| RUSH YPG | 998 (54th) | 1331 (14th) |
| PASS YPG | 2027 (4th) | 1448 (42nd) |
Defensive NCAA Football Stats
| Stat | Ohio State | Indiana |
|---|---|---|
| PPG ALLWD | 79 (42nd) | 71 (36th) |
| TO | 4 (5th) | 4 (5th) |
| SACKS | 9 (14th) | 20 (3rd) |
Ohio State vs. Indiana Head-to-Head Trends for Our AI Prediction
- In the 2025 season, Indiana won against Ohio State with a score of 13-10, covering the spread as +3.5 underdogs.
- Ohio State covered the spread of +10.5 in their 38-15 win over Indiana during the 2024 season.
- During the 2023 season, Indiana covered the spread of +30.5 despite losing to Ohio State 23-3.
- The total went under 45.5 in the 2025 game between Ohio State and Indiana.
Ohio State Buckeyes vs. Indiana Hoosiers NCAA Football Betting Trends
Before locking in your pick for the Ohio State Buckeyes vs. Indiana Hoosiers matchup, take a look at some key betting trends. Indeed, both teams have shown strong patterns in specific spots — and these stats could help uncover where the value lies on today’s NCAA football betting card.
- Ohio State is 27-3 straight up as a favorite in their last 30 games.
- The Buckeyes have a 9-2 record against the spread in games with totals of 50 or more in their last 11 games.
- Ohio State is 25-5 straight up after a win in their last 30 games.
- Indiana is a perfect 20-0 straight up at home in their last 20 games.
- Also, the Hoosiers have a 6-1 record against the spread as an underdog in their last 7 games.
- Additionally, Indiana is 28-1 straight up after a win in their last 29 games.
Ohio State Injury Report
| Player | Status | Injury |
|---|---|---|
| Phillip Daniels (OL) | Questionable | |
| Christian Alliegro (LB) | Questionable | |
| Brandon Inniss (WR) | Questionable | |
| Austin Siereveld (OL) | Questionable | |
| Devin McCuin (WR) | Questionable | |
| Leroy Roker III (S) | Questionable | |
| Anthony Rogers (RB) | Questionable | |
| Vasean Washington (OL) | Questionable | |
| Jaxon Powell (OL) | Questionable | |
| Khary Wilder (DE) | Questionable | |
| Jay Timmons (CB) | Questionable | |
| Amari Valerio-Hudson (WR) | Questionable |
Indiana Injury Report
| Player | Status | Injury |
|---|---|---|
| Khobie Martin (RB) | Out | Forearm |
| Carson Williams (DB) | Out | |
| Lebron Bond (WR) | Questionable | |
| Andrew Barker (TE) | Questionable |
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Today’s Ohio State at Indiana AI Computer Pick
NCAA Football Free Score Prediction: Buckeyes 27 – Hoosiers 24 (Bet Now!) Our AI likes Buckeyes to win by 3.
NEXT NCAA FOOTBALL AI PICK
Considering Ohio State’s strong offensive stats and their recent win over Maryland, they have a slight edge. Indiana’s perfect home record and solid defense make this a close game, but Ohio State’s overall strength gives them the nod.
Not sure what amount to bet on this Ohio State at Indiana AI NCAA Football prediction? Just like our experts we give star ratings on our plays. So far, these AI NCAA football computer picks are rated 4*.
- 1% of your bankroll for 4* or less.
- 2% for 5* and 6*.
- Also, 4% for 7* or higher.
Expert NCAA Football Betting Picks
Need a few more angles for this week’s college football slate? Browse today’s featured premium plays from CappersPicks handicappers, with sides, totals, moneylines, and other NCAA football bets.
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Ohio State at Indiana Odds for Our AI Computer Prediction
Below are the updated Ohio State at Indiana NCAA football odds used by our AI prediction model.
Free NCAA Football AI Computer Picks & Predictions
With 20+ years of CappersPicks handicapping data, our AI prediction model analyzes NCAA football matchups, betting trends and odds to produce free NCAA football computer picks and score predictions. Check back daily for our latest AI NCAA football picks, including today’s Ohio State Buckeyes at Indiana Hoosiers AI prediction.
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