Free AI MLB Prediction: Tigers at Guardians Odds
If you’re searching for Detroit Tigers at Cleveland Guardians AI computer MLB baseball free predictions look no further! This game takes place on Thursday, September 25th at Progressive Field, in Cleveland. At this time, our AI MLB computer prediction model has the gambling analysis, baseball betting trends, and outcome locked in. In fact, when you’re ready, just scroll down to get the free AI MLB pick.
MLB Handicapping – Detroit Tigers at Cleveland Guardians AI MLB Baseball Prediction
- (85-73) Detroit Tigers at Cleveland Guardians (86-72)
- MLB Starting Pitchers: TBD vs. Parker Messick
- Date: Thursday, September 25th
- Time: 6:40 PM ET
- Venue: Progressive Field Cleveland, OH
- MLB Moneyline Odds: Tigers +140 | Guardians -168 (Bet Now!)
- Runline MLB Odds: Tigers +1.5 | Guardians -1.5
- MLB Betting Total: O/U: 8
As can be seen, artificial intelligence (AI) is used by CappersPicks.com to sort through vast quantities of data and identify the best outcomes for free computer picks on MLB baseball betting each day. For one thing, we save you tons of time and energy researching your selections by giving you our daily AI best bets. In fact, scroll down for today’s Detroit Tigers at Cleveland Guardians AI MLB prediction.
Tigers vs. Guardians Starting Lineups
The projected starting lineups for the Detroit Tigers at Cleveland Guardians game today offers plenty of insight into how each club plans to attack this matchup. Additionally, keep an eye on roster shifts, platoon advantages, and lineup depth before placing your MLB bets.
| Player Name | Batting Order | Position |
|---|---|---|
| Jahmai Jones | 1 | DH |
| Gleyber Torres | 2 | 2B |
| Wenceel Pérez | 3 | CF |
| Spencer Torkelson | 4 | 1B |
| Riley Greene | 5 | LF |
| Andy Ibáñez | 6 | 3B |
| Dillon Dingler | 7 | C |
| Zach McKinstry | 8 | RF |
| Javier Báez | 9 | SS |
| Starting Pitcher | – | SP |
| Player Name | Batting Order | Position |
|---|---|---|
| Steven Kwan | 1 | LF |
| Angel Martínez | 2 | CF |
| José Ramírez | 3 | 3B |
| George Valera | 4 | DH |
| Kyle Manzardo | 5 | 1B |
| Gabriel Arias | 6 | SS |
| C.J. Kayfus | 7 | RF |
| Brayan Rocchio | 8 | 2B |
| Austin Hedges | 9 | C |
| Starting Pitcher | – | SP |
Tigers vs. Guardians AI Last Five Head To Head Trends
- In the 2025 regular season, the Guardians have a 3-0 record against the Tigers.
- The Guardians have covered the run line in 2 of the last 3 games this season.
- The total has gone under in 2 of the last 3 games this season.
- In the last 10 games of the 2025 regular season, the total has gone under in 6 games.
Detroit Tigers vs. Cleveland Guardians MLB Betting Trends
Before locking in your pick for the Detroit Tigers vs. Cleveland Guardians matchup, take a look at some key betting trends. Indeed, both teams have shown strong patterns in specific spots — and these stats could help uncover where the value lies on today’s MLB betting card.
- The Tigers are 1-9 straight up in their last 10 games.
- The Guardians have a strong 9-1 straight up record in their last 10 games.
- The Tigers are 0-5 on the runline in their last 5 games.
- Also, the Guardians have covered the runline in 8 of their last 10 games.
- Additionally, the Tigers have hit the over in 5 of their last 10 games.
- The Guardians have gone under the total in 8 of their last 10 games.
Tigers Injury Report
| Player | Status | Injury |
|---|---|---|
| Javier Báez (CF) | Day-to-Day | Neck |
| Alex Cobb (SP) | Out | Hip |
| Matt Vierling (CF) | Out | Oblique |
| Jason Foley (RP) | Out | Shoulder |
| Colt Keith (2B) | Out | Rib |
| Reese Olson (SP) | Out | Shoulder |
| Jackson Jobe (SP) | Out | Elbow |
| Ty Madden (SP) | Out | Shoulder |
| Sean Guenther (RP) | Out | Hip |
| Beau Brieske (RP) | Out | Forearm |
| Sawyer Gipson-Long (SP) | Out | Neck |
Guardians Injury Report
| Player | Status | Injury |
|---|---|---|
| Sam Hentges (RP) | Out | Shoulder |
| Ben Lively (SP) | Out | Forearm |
| Nolan Jones (RF) | Out | Oblique |
| Lane Thomas (CF) | Out | Foot |
| John Means (SP) | Out | Elbow |
| David Fry (1B) | Out | Face |
| Emmanuel Clase (RP) | Out | Personal |
| Will Brennan (RF) | Out | Forearm |
| Franco Aleman (RP) | Out | Hernia |
| Nic Enright (RP) | Out | Elbow |
| Luis L. Ortiz (SP) | Out | Personal |
| Andrew Walters (RP) | Out | Lat |
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Today’s Free Tigers at Guardians MLB Free AI Pick
MLB Free Score Prediction: Tigers 2 – Guardians 5 (Bet Now!) Our AI likes Guardians to win by 3.
NEXT MLB BASEBALL AI PICK
Not sure what amount to bet on this Tigers at Guardians AI MLB prediction? Just like our experts we give star ratings on our plays. So far, these AI MLB computer picks are rated 4*.
- 1% of your bankroll for 4* or less.
- 2% for 5* and 6*.
- Also, 4% for 7* or higher.
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Odds Comparison: Detroit Tigers at Cleveland Guardians
Below are the updated Detroit vs. Cleveland MLB odds used by our AI prediction model.
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