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NCAA Football

Sportsbook.com: USC vs. Notre Dame Preview

CFB: Trojans to continue dominance?

There is a long and rich history in the head-to-head series between Notre Dame & USC, and it will renew on Saturday in South Bend.

It is a huge game for the Irish, who have a chance to post the biggest signature win in the Charlie Weis era.

Snapping their winless bowl skid last December, is this the time they finally make themselves relevant again on the national football stage? Oddsmakers at Sportsbook.com don’t seem to think so, setting up USC as the 11-point road favorite.