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Seahawks vs. Colts Trends + Week 4 Pick

NFL Game Day Picks: Seahawks to fall to Peyton and the Colts

Seattle Seahawks (+10½) vs. Indianapolis Colts (-10½)
O/U (44)
Sunday, October 4 1:00 PM ET

The Seattle Seahawks (1-2 SU, 1-2 ATS, 1-2 O/U) will be looking to avoid a third consecutive loss while the Indianapolis Colts (3-0 SU, 2-1 ATS, 1-2 O/U) will try to keep their unblemished record intact when the two teams square off on Sunday at Lucas Oil Stadium at 1 PM ET.