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Point Spreads

Week 8 Spreads: San Francisco vs. Indianapolis

The Keys to Win: 49ers vs Colts

San Francisco 49ers @ Indianapolis Colts
Sunday, November 1st – Lucas Oil Stadium – Indianapolis, IN
NFL Point Spread: Colts -12, O/U: 44

The 49ers found some life last week, despite losing by three in Houston against the Texans. Quarterback Alex Smith, filling in for an ineffective Shaun Hill, rallied coach Mike Singletary’s squad to three touchdowns, but a late interception sealed the 49ers’ fate in the heart of Texas.