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NFL Week 10 Handicapping Tips

NFL Week 10 Match Ups

In a potential preview of this year’s AFC Championship game, the New England Patriots travel to Indianapolis to play the Colts on Sunday night. This game over the past several years has become one of the biggest rivalries in the NFL. After completely dominating the Colts over the first half of the decade, New England has now lost four of last five meetings between these two teams. Some other big games include Cincinnati at Pittsburgh, Seattle at Arizona, and Philadelphia at San Diego.