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Week 5 Patriots vs. 49ers NFL Predictions

NFL Football Betting – New England Patriots at San Francisco 49ers

The New England Patriots (2-1 SU, 1-2 ATS), smarting from their first loss of the season, will try to bounce back on Sunday when they take on the San Francisco 49ers (2-2 SU & ATS) in NFL action that is slated to kick off at 4:15 PM ET at Candlestick Park (natural turf) in San Francisco.