South Florida Bulls @ Louisville Cardinals

The Big East is struggling to provide the big matchups that the other conferences are providing but that doesn’t mean you can’t look there for profits. The Bulls travel to Kentucky looking to back up last year’s impressive 55-17 dismantling of Louisville with another dominating performance.

South Florida, 6-1 straight up but just 2-4 against the spread, has failed to cover because they have taken opponents lightly throughout the season but they may finally have realized that they need big victories to impress the pollsters. Backing up a 45-13 win over Syracuse with another big win over a conference foe is a move in the right direction.

Pick: South Florida -3.5

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